Last updated on February 2019

Psilocybin for the Treatment of Migraine Headache

Brief description of study

The purpose of this study is to investigate the effects of oral psilocybin in migraine headache. Subjects will each receive a dose of placebo and a dose of psilocybin approximately 14 days apart. Subjects will be randomized to the order of treatment and they will be randomized to receive either low or high dose psilocybin. Subjects will maintain a headache diary prior to, during, and after the treatments in order to document headache frequency and intensity, as well as associated symptoms, in both the short and long-term.

Clinical Study Identifier: NCT03341689

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Recruitment Status: Open

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