Last updated on July 2019

A Study Comparing the Efficacy and Safety of Polatuzumab Vedotin With Rituximab-Cyclophosphamide Doxorubicin and Prednisone (R-CHP) Versus Rituximab-Cyclophosphamide Doxorubicin Vincristine and Prednisone (R-CHOP) in Participants With Diffuse Large B-Cell Lymphoma


Brief description of study

This Phase III, randomized, double-blind, placebo-controlled study will compare the efficacy, safety, and pharmacokinetics of polatuzumab vedotin plus R-CHP versus R-CHOP in participants with previously untreated diffuse large B-cell lymphoma (DLBCL).

Clinical Study Identifier: NCT03274492

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Southern Cancer Center

Daphne, AL United States
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City of Hope

Duarte, CA United States
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Florida Cancer Specialists

West Palm Beach, FL United States
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Illinois Cancer Specialists

Arlington Heights, IL United States
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University of Maryland

Baltimore, MD United States
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Johns Hopkins University

Baltimore, MD United States
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Karmanos Cancer Center

Detroit, MI United States
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HCA Midwest Division

Kansas City, MO United States
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Shenandoah Oncology Associates

Winchester, VA United States
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North Star Lodge

Yakima, WA United States
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Texas Oncology-Tyler

Irving, TX United States
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Queen Mary Hospital

Hong Kong, Hong Kong
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Palmerston North Hospital

Roslyn Palmerston North, Israel
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Severance Hospital

Seoul, Korea, Republic of
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Samsung Medical Center

Seoul, Korea, Republic of
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Waikato Hospital

Hamilton, New Zealand
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CHU UCL Mont-Godinne

Mont-godinne, Belgium
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CHU Angers

Angers, France
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CHU de Brabois

Vandoeuvre Les Nancy, France
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Ochsner Medical Center

New Orleans, LA United States
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CH Metropole de Savoie

CHAMBERY Cedex, France
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CHD Vend e

La Roche Sur Yon, France
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Institut de Cancerologie

St Priest en Jarez, France
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UZ Gent

Gent, Belgium
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Fakultni nemocnice Ostrava

Ostrava - Poruba, Czechia
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Recruitment Status: Open


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