Last updated on December 2018

Encopresis & MIE (DoD #2)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Functional encopresis | Pervasive developmental disorder
  • Age: Between 5 - 12 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Males and females > 5 years of age and 12 years 11 months of age.
  • Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 diagnosis of Autism Spectrum Disorder as established by clinical assessment, corroborated by the Autism Diagnostic Observational Schedule.
  • Less than 60% of days are continent days or more than 1 day out of 7 is an incontinent day over the past two weeks (Continent day is defined as a day with at least one continent bowel movement and no incontinence. Incontinent day is a day with an incontinent bowel movement regardless of whether a continent bowel movement also occurs)..
  • Medication free or on stable medication (no changes in past 6 weeks and no planned changes for the next 6 months).
  • Urine continent - one or fewer episodes of incontinent urination each day

Exclusion Criteria:

  • Presence of a known medical condition in the child (based on medical history or physical examination) that would interfere with child's ability to control his/her anus. These include: History of any anal surgery, spinal dysraphism (e.g., spina bifida), other neurologic disorder affecting anal function, and prolonged/recurrent gastrointestinal infectious disease (e.g. Clostridium difficile colitis). In addition, the following may constitute exclusions following evaluation by a physician: Inflammatory bowel disease, short gut syndrome, chronic diarrhea, or history of intestinal/abdominal surgery.
  • Presence of a current serious behavioral problem or psychiatric condition that would require another treatment (e.g., psychotic disorder, major depression, moderate or greater aggression, severe disruptive behavior), based on information collected at screening and the Behavior Problems Inventory-01 (BPI-01).
  • Currently receiving and caregiver refusal to discontinue ongoing behavioral or alternative medical intervention for encopresis.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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