Development of Diagnostics and Treatment of Urological Cancers (DEDUCER)

  • STATUS
    Recruiting
  • End date
    Dec 15, 2025
  • participants needed
    100
  • sponsor
    Helsinki University Central Hospital
Updated on 31 January 2022
cancer
urinary tract cancer

Summary

The purpose of the study is to evaluate whether state-of-the-art technologies such and next generation sequencing and drug sensitivity and resistance testing of patient derived tumour tissue can facilitate research translation and improve outcome of urologic cancers.

Description

Access to high-quality clinical patient material (e.g. tissue of primary tumor and metastasis, plasma and urine) linked to comprehensive registry and clinical data and molecular characterization of the patient material using state-of-the-art technologies (e.g. NGS, transcriptomics, imaging, DSRT) will facilitate a more rapid translation of basic research innovations into clinical care (diagnostics, imaging, therapeutics) and result in improved outcome of patients suffering from urologic cancers ("personalized medicine").

The principal aim of the project is to establish a framework and infrastructure for the systematic collection and interpretation of biological patient samples. Similarly, the investigators aim to establish the format how the related clinical and research data can be made readily accessible for both clinicians and researchers without compromising patient privacy. The key objectives of the project are to facilitate research translation and to improve outcome of urologic cancers.

Details
Condition Prostate Carcinoma, Kidney Cancer, Urothelial Carcinoma, Testicular Cancer, Penile Cancer
Treatment Personalised treatment
Clinical Study IdentifierNCT02994758
SponsorHelsinki University Central Hospital
Last Modified on31 January 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

The patient is able to provide written informed consent and is at least 18 years of age
The patient must have a verified diagnosis of an urologic cancer by a board-certified clinician

Exclusion Criteria

The patient is not willing to provide a written informed consent
The patient has a severe psychiatric illness, imprisonment or mental impairment inflicting on ability to give informed consent
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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