Last updated on November 2017

A Phase III randomized, placebo-controlled, double-blind trial of Sorafenib plus Erlotinib vs. Sorafenib plus Placebo as First Line systemic treatment for Hepatocellular Carcinoma (HCC)


Brief description of study

A Phase III randomized, placebo-controlled, double-blind trial of Sorafenib plus Erlotinib vs. Sorafenib plus Placebo as First Line systemic treatment for Hepatocellular Carcinoma (HCC)

Detailed Study Description

This is a randomized trial to evaluate the clinical benefit of sorafenib 400 mg twice daily and erlotinib 150 mg once a day versus sorafenib 400 mg twice daily and placebo erlotinib once daily in subjects with unresectable advanced or metastatic Child-Pugh A HCC. Patients who are candidates for potentially curative intervention (i.e. surgical resection or local ablation) are not eligible for this study.

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Clinical Study Identifier: TX15681

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Additional Locations, XX Australia

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Additional Locations, XX Austria

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Additional Locations, XX Belgium

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Additional Locations, XX Brazil

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Additional Locations, XX Canada

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Additional Locations, XX Chile

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Additional Locations, XX China

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Additional Locations, XX France

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Additional Locations, XX Germany

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Additional Locations, XX Greece

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Additional Locations, XX Israel

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Additional Locations, XX Italy

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Additional Locations, XX Poland

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Additional Locations, XX Russian Federation

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Additional Locations, XX South Africa

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Additional Locations, XX Spain

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Additional Locations, XX United Kingdom

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Additional Locations, CA USA

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Additional Locations, FL USA

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Additional Locations, GA USA

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Additional Locations, IL USA

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Additional Locations, KY USA

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Additional Locations, LA USA

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Additional Locations, MA USA

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Additional Locations, MO USA

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Additional Locations, NM USA

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Additional Locations, NY USA

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Additional Locations, NC USA

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Additional Locations, PA USA

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Additional Locations, TX USA

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Additional Locations, VA USA

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Additional Locations, WA USA

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Additional Locations, XX Bulgaria

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Additional Locations, XX Colombia

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Additional Locations, XX Hong Kong

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Additional Locations, XX Republic of Korea

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Additional Locations, XX New Zealand

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Additional Locations, XX Peru

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Additional Locations, XX Singapore

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Additional Locations, XX Taiwan

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Additional Locations, DC USA

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Additional Locations, HI USA

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Additional Locations, KS USA

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Additional Locations, MD USA

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Additional Locations, MI USA

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Additional Locations, MN USA

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Additional Locations, OH USA

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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