Positron Emission Tomography (PET) Imaging With Zirconium-89 (89Zr)-Trastuzumab for Prediction of HER2 Targeted Therapy Effectiveness
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- STATUS
- Recruiting
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- End date
- Jan 26, 2025
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- participants needed
- 10
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- sponsor
- University of Alabama at Birmingham
Summary
Our goal is to investigate the use of 89Zr-trastuzumab as a HER2 imaging agent to determine which patients are likely to respond to targeted HER2 agents as single agent therapy. We are proposing to perform a pilot study with goals of demonstrating the feasibility of imaging breast cancer patients with 89Zr-trastuzumab-PET/MRI, evaluating the relationship between tumor 89Zr-trastuzumab uptake and in vitro positivity of HER2, assessing the relationship between 89Zr-trastuzumab uptake and response to HER2 therapy.
Details
| Condition | Breast Cancer |
|---|---|
| Treatment | [89Zr]-Df-Trastuzumab, PET/MRI Imaging |
| Clinical Study Identifier | NCT03321045 |
| Sponsor | University of Alabama at Birmingham |
| Last Modified on | 26 March 2022 |
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