Last updated on November 2019

A Study of RO7198457 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Brief description of study

This is a Phase 1a/1b, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, immune response, and pharmacokinetics of RO7198457 as a single agent and in combination with atezolizumab (MPDL3280A, an engineered anti-programmed death-ligand 1 [anti-PD-L1] antibody).

Clinical Study Identifier: NCT03289962

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The Angeles Clinic

Los Angeles, CA United States
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UCSF Comprehensive Cancer Ctr

San Francisco, CA United States
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Stanford Cancer Center

Stanford, CA United States
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University of Colorado

Aurora, CO United States
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Georgetown University

Washington, WA United States
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Dana Farber Can Ins

Boston, MA United States
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Sarah Cannon Res Inst; TN Onc

Nashville, TN United States
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UZ Gent

Gent, Belgium
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Leiden, Netherlands
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