Extension Carbidopa-levodopa in Neovascular AMD

  • STATUS
    Not Recruiting
  • participants needed
    52
  • sponsor
    Snyder, Robert W., M.D., Ph.D., P.C.
Updated on 5 December 2022
levodopa
neovascularization
carbidopa-levodopa
vitamins

Summary

This protocol is an extension of protocol 0002, Proof of Concept and Dose Ranging Study of carbidopa-levodopa in Neovascular AMD. that is a 3 month study of escalating doses of carbidopa-levodopa in neovascular AMD. This trial is a 9 month extension for patients who successfully complete protocol 0002 and wish to continue carbidopa-levodopa therapy. It will use the two higher dose regimens of protocol 0002. these will be assigned according to how well the higher dose was tolerated in protocol 0002.

Description

This extension will employ the same medications, measurements, guidelines for anti-VEGF injections and safeguards as in protocol 0002. In combination with protocol 0002, it will provide a total of 12 months of therapy with carbidopa-levodopa.

Details
Condition Retina, Retinopathy, Macula; Degeneration
Treatment carbidopa-levodopa 25-100 mg
Clinical Study IdentifierNCT03197493
SponsorSnyder, Robert W., M.D., Ph.D., P.C.
Last Modified on5 December 2022

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