Potassium Supplementation in CKD
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- STATUS
- Recruiting
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- End date
- Oct 1, 2023
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- participants needed
- 532
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- sponsor
- Erasmus Medical Center
Summary
The current high-sodium, low-potassium diet contributes to the high prevalence of high blood pressure (hypertension). Indeed, the anti-hypertensive effects of potassium supplementation are well-established. Hypertension is even more prevalent and resistant in patients with chronic kidney disease (CKD) and contributes to further decline in kidney function. Four recent epidemiological studies (published 2014 - 2016) showed that higher dietary potassium intake was associated with better renal outcomes. All studies recommended an intervention study with potassium supplementation in patients with CKD, but this has not been performed. The aim of this study is to study the renoprotective effect of potassium supplementation in patients with CKD (stage 3b or 4, i.e. estimated glomerular filtration rate [eGFR] 15 - 45 ml/min/1.73 m2).
Details
| Condition | chronic renal insufficiency, Vascular Diseases, Hyperkalemia, Hypokalemia, Hypertension, Diabetes and Hypertension, High Blood Pressure (Hypertension), High Blood Pressure (Hypertension - Pediatric), Elevated Blood Pressure, high blood pressure, arterial hypertension |
|---|---|
| Treatment | Placebo, potassium citrate, Potassium Chloride, Potassium Chloride |
| Clinical Study Identifier | NCT03253172 |
| Sponsor | Erasmus Medical Center |
| Last Modified on | 23 January 2021 |
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