Last updated on March 2019

Esmolol to Control Adrenergic Storm in Septic Shock- ROLL-IN 2


Brief description of study

Septic shock is a common syndrome caused by the body's response to an infection. Septic shock is responsible for 10% of all ICU admissions and 30% of ICU deaths. Use of "beta blocker" medications may improve outcomes after septic shock. This pilot study evaluates protocols to infuse the beta blocker esmolol in patients with septic shock.

Detailed Study Description

This is a prospective, single arm, feasibility study of esmolol infusion in septic shock. The objective is to evaluate the feasibility, adequacy, and efficiency of study protocols for a subsequent ECASSS study. This study (ECASSS-R2) extends observations made in an initial pilot, ECASSS-R.

Clinical Study Identifier: NCT03208257

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Intermountain Medical Center

Murray, UT United States
6.28miles
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