Pulmonary Rehabilitation in Idiopathic Pulmonary Fibrosis

  • STATUS
    Recruiting
  • End date
    Sep 2, 2022
  • participants needed
    20
  • sponsor
    Corfu General Hospital
Updated on 2 February 2021
nintedanib
pulmonary rehabilitation
idiopathic pulmonary fibrosis
pirfenidone

Summary

This is an interventional double-blind randomized controlled trial, to investigate the short and long-term effects of a supervised exercise training program in patients with IPF, depending on alternate patterns of oxygen supplementation during PR.

Description

The investigators hypothesize that PR service with supplemented oxygen supply regardless of hypoxemia may have significantly better short-term effects in patients with IPF. The study will take place in Corfu General Hospital, by the Departments of Pulmonary Medicine and Physiotherapy and Rehabilitation, respectively. Study participants will be divided in two equal arms 1:1 in a double-blind manner. One of the investigators blinded to their clinical data will assign each participant to PR service either i) with constant supplementary oxygen supply FiO2 50% regardless of saturation status Group A) or ii) without oxygen supply unless upon resting or exercise induced hypoxemia (saturation <88%) (Group B).

Details
Condition Pulmonary Fibrosis, Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, usual interstitial pneumonia
Treatment Pulmonary rehabilitation
Clinical Study IdentifierNCT03326089
SponsorCorfu General Hospital
Last Modified on2 February 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

diagnosis of IPF based on current established criteria
no exacerbation previous 3 months
no participation in such program previous 3 months
If on treatment with pirfenidone or nintedanib, this will be recorded and patient should be on treatment for at least 3-6 months to achieve stable state

Exclusion Criteria

concomitant diagnosis of congestive heart failure and lung cancer
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