Last updated on March 2019

Metformin Vitamin D and Depression in Polycystic Ovary Syndrome (PCOS) Trial

Brief description of study

Open-label randomized clinical trial assessing the efficacy of Metformin versus Vitamin D in improving symptoms of depressed mood in polycystic ovary syndrome.

Detailed Study Description

This is a single center, open-label, randomized, pilot clinical trial. Women with polycystic ovary syndrome and depressed mood, who are insulin resistant and vitamin D insufficient are eligible. Subjects are randomly assigned to one of two interventions: Vitamin D versus metformin. Subjects are followed with questionnaires and a final wrap-up clinic visit with a physician. The study duration is 12 weeks.

Clinical Study Identifier: NCT03380091

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UCSF Center for Reproductive Health

San Francisco, CA United States
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