Last updated on March 2019

Azacitidine With or Without Nivolumab or Midostaurin or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome


Brief description of study

This randomized phase II/III trial studies how well azacitidine with or without nivolumab or midostaurin, or decitabine and cytarabine alone work in treating older patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome. Drugs used in chemotherapy, such as azacitidine, decitabine, and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as nivolumab, may interfere with the ability of cancer cells to grow and spread. Midostaurin may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving azacitidine with or without nivolumab or midostaurin, or decitabine and cytarabine alone may kill more cancer cells.

Detailed Study Description

PRIMARY OBJECTIVES:

I. To select, based on overall survival, any or all of the "Novel Therapeutic" regimens for further testing against azacitidine in patients age 60 and older with newly diagnosed acute myeloid leukemia (AML) or myelodysplastic syndrome with excessive blasts-2 (MDS-EB-2). (Phase II) II. To compare overall survival of the "Novel Therapeutic" regimens selected in the phase II portion of the trial to azacitidine in these patient populations. (Phase III)

SECONDARY OBJECTIVES:

I. To estimate the frequency and severity of toxicities of the regimens in these patient populations.

II. To estimate response rates, event-free survival, and relapse-free survival for these regimens in these patient populations.

TERTIARY OBJECTIVES:

I. To investigate associations between cytogenetic and molecular abnormalities (including FLT3) and outcomes for each of the regimens in these patient populations.

II. To bank specimens for future correlative studies.

OUTLINE: Patients are randomized to 1 of 4 arms.

ARM A: Patients receive azacitidine subcutaneously (SC) or intravenously (IV) daily on days 1-7 or days 1-5 and 8-9. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

ARM B: Patients receive azacitidine as in Arm A and nivolumab IV over 30-60 minutes on days 1 and 15. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

ARM C: Patients receive azacitidine as in Arm A and midostaurin orally (PO) twice daily (BID) on days 8-21. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

ARM D:

INDUCTION: Patients receive decitabine IV over 2 hours on days 1-5 and cytarabine IV continuously on days 6-11. Treatment repeats every 28 days for up to 2 courses in the absence of disease progression or unacceptable toxicity.

MAINTENANCE: Patients deemed stable at the discretion of the treating physician receive decitabine as in Induction. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3 months for 1 year, every 6 months for 2 years, then annually for 2 years.

Clinical Study Identifier: NCT03092674

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Kootenai Medical Center

Coeur d'Alene, ID United States

Kootenai Cancer Center

Post Falls, ID United States

Kootenai Cancer Clinic

Sandpoint, ID United States

Community Hospital of Anaconda

Anaconda, MT United States

Billings Clinic Cancer Center

Billings, MT United States

Bozeman Deaconess Hospital

Bozeman, MT United States

Benefis Healthcare- Sletten Cancer Institute

Great Falls, MT United States

Great Falls Clinic

Great Falls, MT United States

Saint Peter's Community Hospital

Helena, MT United States

Kalispell Regional Medical Center

Kalispell, MT United States

Community Medical Hospital

Missoula, MT United States

Billings Clinic-Cody

Cody, WY United States

Anchorage Associates in Radiation Medicine

Anchorage, AK United States

Alaska Breast Care and Surgery LLC

Anchorage, AK United States

Alaska Oncology and Hematology LLC

Anchorage, AK United States

Alaska Women's Cancer Care

Anchorage, AK United States

Anchorage Oncology Centre

Anchorage, AK United States

Katmai Oncology Group

Anchorage, AK United States

Providence Alaska Medical Center

Anchorage, AK United States

CHI Saint Vincent Cancer Center Hot Springs

Hot Springs, AR United States

Penrose-Saint Francis Healthcare

Colorado Springs, CO United States

Rocky Mountain Cancer Centers-Penrose

Colorado Springs, CO United States

Porter Adventist Hospital

Denver, CO United States

Mercy Medical Center

Durango, CO United States

Southwest Oncology PC

Durango, CO United States

Mountain Blue Cancer Care Center

Golden, CO United States

Rocky Mountain Cancer Centers-Lakewood

Lakewood, CO United States

Saint Anthony Hospital

Lakewood, CO United States

Littleton Adventist Hospital

Littleton, CO United States

Longmont United Hospital

Longmont, CO United States

Rocky Mountain Cancer Centers-Longmont

Longmont, CO United States

Parker Adventist Hospital

Parker, CO United States

Rocky Mountain Cancer Centers-Parker

Parker, CO United States

Saint Mary Corwin Medical Center

Pueblo, CO United States

Rocky Mountain Cancer Centers - Pueblo

Pueblo, CO United States

Rocky Mountain Cancer Centers-Thornton

Thornton, CO United States

Mayo Clinic in Florida

Jacksonville, FL United States

Sacred Heart Hospital

Pensacola, FL United States

Illinois CancerCare-Bloomington

Bloomington, IL United States

Illinois CancerCare-Canton

Canton, IL United States

Memorial Hospital of Carbondale

Carbondale, IL United States

SIH Cancer Institute

Carterville, IL United States

Illinois CancerCare-Carthage

Carthage, IL United States

Centralia Oncology Clinic

Centralia, IL United States

Decatur Memorial Hospital

Decatur, IL United States

Crossroads Cancer Center

Effingham, IL United States

Illinois CancerCare-Eureka

Eureka, IL United States

Illinois CancerCare-Galesburg

Galesburg, IL United States

Western Illinois Cancer Treatment Center

Galesburg, IL United States

Illinois CancerCare-Kewanee Clinic

Kewanee, IL United States

Illinois CancerCare-Macomb

Macomb, IL United States

Illinois CancerCare-Ottawa Clinic

Ottawa, IL United States

Illinois CancerCare-Pekin

Pekin, IL United States

Methodist Medical Center of Illinois

Peoria, IL United States

Illinois CancerCare-Peoria

Peoria, IL United States

OSF Saint Francis Medical Center

Peoria, IL United States

Illinois CancerCare-Peru

Peru, IL United States

Valley Radiation Oncology

Peru, IL United States

Illinois CancerCare-Princeton

Princeton, IL United States

SwedishAmerican Regional Cancer Center/ACT

Rockford, IL United States

Southern Illinois University School of Medicine

Springfield, IL United States

Springfield Clinic

Springfield, IL United States

Memorial Medical Center

Springfield, IL United States

Mercy Cancer Center-West Lakes

Clive, IA United States

Alegent Health Mercy Hospital

Council Bluffs, IA United States

Greater Regional Medical Center

Creston, IA United States

Iowa Methodist Medical Center

Des Moines, IA United States

Broadlawns Medical Center

Des Moines, IA United States

Mercy Medical Center - Des Moines

Des Moines, IA United States

Iowa Lutheran Hospital

Des Moines, IA United States

Methodist West Hospital

West Des Moines, IA United States

Mercy Medical Center-West Lakes

West Des Moines, IA United States

Flaget Memorial Hospital

Bardstown, KY United States

Commonwealth Cancer Center-Corbin

Corbin, KY United States

Saint Joseph Hospital East

Lexington, KY United States

Saint Joseph London

London, KY United States

Jewish Hospital

Louisville, KY United States

Saints Mary and Elizabeth Hospital

Louisville, KY United States

Jewish Hospital Medical Center Northeast

Louisville, KY United States

Jewish Hospital Medical Center South

Shepherdsville, KY United States

Ochsner Medical Center Jefferson

New Orleans, LA United States

Eastern Maine Medical Center

Bangor, ME United States

Lafayette Family Cancer Center-EMMC

Brewer, ME United States

Henry Ford Cancer Institute Downriver

Brownstown, MI United States

Henry Ford Macomb Hospital-Clinton Township

Clinton Township, MI United States

Henry Ford Medical Center-Fairlane

Dearborn, MI United States

Henry Ford Hospital

Detroit, MI United States

Allegiance Health

Jackson, MI United States

Henry Ford Medical Center-Columbus

Novi, MI United States

Henry Ford West Bloomfield Hospital

West Bloomfield, MI United States

Sanford Clinic North-Bemidgi

Bemidji, MN United States

Essentia Health Cancer Center

Duluth, MN United States

Miller-Dwan Hospital

Duluth, MN United States

Lake Region Healthcare Corporation-Cancer Care

Fergus Falls, MN United States

Mayo Clinic

Rochester, MN United States

Essentia Health Virginia Clinic

Virginia, MN United States

Parkland Health Center-Bonne Terre

Bonne Terre, MO United States

Saint Francis Medical Center

Cape Girardeau, MO United States

Southeast Cancer Center

Cape Girardeau, MO United States

Missouri Baptist Medical Center

Saint Louis, MO United States

Sainte Genevieve County Memorial Hospital

Sainte Genevieve, MO United States

Missouri Baptist Sullivan Hospital

Sullivan, MO United States

Missouri Baptist Outpatient Center-Sunset Hills

Sunset Hills, MO United States

Saint Patrick Hospital - Community Hospital

Missoula, MT United States

CHI Health Saint Francis

Grand Island, NE United States

Heartland Hematology and Oncology

Kearney, NE United States

CHI Health Good Samaritan

Kearney, NE United States

Saint Elizabeth Regional Medical Center

Lincoln, NE United States

Alegent Health Immanuel Medical Center

Omaha, NE United States

Hematology and Oncology Consultants PC

Omaha, NE United States

Alegent Health Lakeside Hospital

Omaha, NE United States

Creighton University Medical Center

Omaha, NE United States

Midlands Community Hospital

Papillion, NE United States

Margaret R Pardee Memorial Hospital

Hendersonville, NC United States

Sanford Bismarck Medical Center

Bismarck, ND United States

Roger Maris Cancer Center

Fargo, ND United States

Sanford Broadway Medical Center

Fargo, ND United States

Good Samaritan Hospital - Cincinnati

Cincinnati, OH United States

Bethesda North Hospital

Cincinnati, OH United States

TriHealth Cancer Institute-Westside

Cincinnati, OH United States

TriHealth Cancer Institute-Anderson

Cincinnati, OH United States

University of Oklahoma Health Sciences Center

Oklahoma City, OK United States

Integris Cancer Institute of Oklahoma

Oklahoma City, OK United States

Saint Charles Health System

Bend, OR United States

Clackamas Radiation Oncology Center

Clackamas, OR United States

Bay Area Hospital

Coos Bay, OR United States

Providence Newberg Medical Center

Newberg, OR United States

Providence Portland Medical Center

Portland, OR United States

Providence Saint Vincent Medical Center

Portland, OR United States

Ephrata Cancer Center

Ephrata, PA United States

Ephrata Community Hospital

Ephrata, PA United States

Adams Cancer Center

Gettysburg, PA United States

Cherry Tree Cancer Center

Hanover, PA United States

Sechler Family Cancer Center

Lebanon, PA United States

WellSpan Health-York Cancer Center

York, PA United States

WellSpan Health-York Hospital

York, PA United States

Greenville Memorial Hospital

Greenville, SC United States

Sanford Cancer Center Oncology Clinic

Sioux Falls, SD United States

Sanford USD Medical Center - Sioux Falls

Sioux Falls, SD United States

Memorial Hospital

Chattanooga, TN United States

Memorial GYN Plus

Ooltewah, TN United States

Saint Joseph Regional Cancer Center

Bryan, TX United States

Providence Regional Cancer System-Aberdeen

Aberdeen, WA United States

PeaceHealth Saint Joseph Medical Center

Bellingham, WA United States

Harrison Medical Center

Bremerton, WA United States

Highline Medical Center-Main Campus

Burien, WA United States

Providence Regional Cancer System-Centralia

Centralia, WA United States

Swedish Medical Center-Edmonds

Edmonds, WA United States

Saint Elizabeth Hospital

Enumclaw, WA United States

Providence Regional Cancer Partnership

Everett, WA United States

Saint Francis Hospital

Federal Way, WA United States

Swedish Cancer Institute-Issaquah

Issaquah, WA United States

Kadlec Clinic Hematology and Oncology

Kennewick, WA United States

Providence Regional Cancer System-Lacey

Lacey, WA United States

Saint Clare Hospital

Lakewood, WA United States

PeaceHealth Saint John Medical Center

Longview, WA United States

Pacific Gynecology Specialists

Seattle, WA United States

Swedish Medical Center-Ballard Campus

Seattle, WA United States

Kaiser Permanente Washington

Seattle, WA United States

Swedish Medical Center-First Hill

Seattle, WA United States

Swedish Medical Center-Cherry Hill

Seattle, WA United States

Providence Regional Cancer System-Shelton

Shelton, WA United States

Rockwood Clinic Cancer Treatment Center-Valley

Spokane Valley, WA United States

Rockwood North Cancer Treatment Center

Spokane, WA United States

Northwest Medical Specialties PLLC

Tacoma, WA United States

PeaceHealth Southwest Medical Center

Vancouver, WA United States

Providence Saint Mary Regional Cancer Center

Walla Walla, WA United States

Edwards Comprehensive Cancer Center

Huntington, WV United States

Duluth Clinic Ashland

Ashland, WI United States

Ingalls Memorial Hospital

Harvey, IL United States

Mary Greeley Medical Center

Ames, IA United States

McFarland Clinic PC-Boone

Boone, IA United States

McFarland Clinic PC-Trinity Cancer Center

Fort Dodge, IA United States

McFarland Clinic PC-Jefferson

Jefferson, IA United States

McFarland Clinic PC-Marshalltown

Marshalltown, IA United States

Integris Southwest Medical Center

Oklahoma City, OK United States

Reid Health

Richmond, IN United States

Indu and Raj Soin Medical Center

Beavercreek, OH United States

Dayton Physicians LLC-Miami Valley South

Centerville, OH United States

Miami Valley Hospital South

Centerville, OH United States

Oncology Hematology Care Inc-Kenwood

Cincinnati, OH United States

Good Samaritan Hospital - Dayton

Dayton, OH United States

Miami Valley Hospital

Dayton, OH United States

Dayton Physicians LLC-Samaritan North

Dayton, OH United States

Samaritan North Health Center

Dayton, OH United States

Armes Family Cancer Center

Findlay, OH United States

Blanchard Valley Hospital

Findlay, OH United States

Orion Cancer Care

Findlay, OH United States

Dayton Physicians LLC-Atrium

Franklin, OH United States

Dayton Physicians LLC-Wayne

Greenville, OH United States

Wayne Hospital

Greenville, OH United States

Greater Dayton Cancer Center

Kettering, OH United States

First Dayton Cancer Care

Kettering, OH United States

Kettering Medical Center

Kettering, OH United States

Springfield Regional Cancer Center

Springfield, OH United States

Springfield Regional Medical Center

Springfield, OH United States

Dayton Physicians LLC-Upper Valley

Troy, OH United States

Upper Valley Medical Center

Troy, OH United States

Kaiser Permanente-Fremont

Fremont, CA United States

Fresno Cancer Center

Fresno, CA United States

Kaiser Permanente-Fresno

Fresno, CA United States

Kaiser Permanente-Modesto

Modesto, CA United States

Kaiser Permanente Oakland-Broadway

Oakland, CA United States

Kaiser Permanente-Oakland

Oakland, CA United States

Kaiser Permanente-Rancho Cordova Cancer Center

Rancho Cordova, CA United States

Kaiser Permanente-Redwood City

Redwood City, CA United States

Kaiser Permanente-Richmond

Richmond, CA United States

Rohnert Park Cancer Center

Rohnert Park, CA United States

Kaiser Permanente-Roseville

Roseville, CA United States

Kaiser Permanente-South Sacramento

Sacramento, CA United States

South Sacramento Cancer Center

Sacramento, CA United States

Kaiser Permanente - Sacramento

Sacramento, CA United States

Kaiser Permanente-San Francisco

San Francisco, CA United States

Kaiser Permanente-Santa Teresa-San Jose

San Jose, CA United States

Kaiser Permanente San Leandro

San Leandro, CA United States

Kaiser Permanente-San Rafael

San Rafael, CA United States

Kaiser San Rafael-Gallinas

San Rafael, CA United States

Kaiser Permanente Medical Center - Santa Clara

Santa Clara, CA United States

Kaiser Permanente-Santa Rosa

Santa Rosa, CA United States

Kaiser Permanente Cancer Treatment Center

South San Francisco, CA United States

Kaiser Permanente-South San Francisco

South San Francisco, CA United States

Kaiser Permanente-Stockton

Stockton, CA United States

Kaiser Permanente Medical Center-Vacaville

Vacaville, CA United States

Kaiser Permanente-Vallejo

Vallejo, CA United States

Kaiser Permanente-Walnut Creek

Walnut Creek, CA United States

Kaiser Permanente Moanalua Medical Center

Honolulu, HI United States

Lovelace Medical Center-Saint Joseph Square

Albuquerque, NM United States

University of New Mexico Cancer Center

Albuquerque, NM United States

Presbyterian Kaseman Hospital

Albuquerque, NM United States

University of Rochester

Rochester, NY United States

Siteman Cancer Center at West County Hospital

Creve Coeur, MO United States

Washington University School of Medicine

Saint Louis, MO United States

Siteman Cancer Center-South County

Saint Louis, MO United States

Siteman Cancer Center at Christian Hospital

Saint Louis, MO United States

Cleveland Clinic Foundation

Cleveland, OH United States

Cleveland Clinic Cancer Center Independence

Independence, OH United States

Cleveland Clinic Cancer Center Mansfield

Mansfield, OH United States

Hillcrest Hospital Cancer Center

Mayfield Heights, OH United States

North Coast Cancer Care

Sandusky, OH United States

Cleveland Clinic Cancer Center Strongsville

Strongsville, OH United States

South Pointe Hospital

Warrensville Heights, OH United States

The Watson Clinic

Lakeland, FL United States

McFarland Clinic PC - Ames

Ames, IA United States

Fairview Ridges Hospital

Burnsville, MN United States

Mercy Hospital

Coon Rapids, MN United States

Fairview-Southdale Hospital

Edina, MN United States

Unity Hospital

Fridley, MN United States

Fairview Maple Grove Medical Center

Maple Grove, MN United States

Minnesota Oncology Hematology PA-Maplewood

Maplewood, MN United States

Abbott-Northwestern Hospital

Minneapolis, MN United States

Hennepin County Medical Center

Minneapolis, MN United States

Health Partners Inc

Minneapolis, MN United States

New Ulm Medical Center

New Ulm, MN United States

North Memorial Medical Health Center

Robbinsdale, MN United States

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, MN United States

Regions Hospital

Saint Paul, MN United States

United Hospital

Saint Paul, MN United States

Saint Francis Regional Medical Center

Shakopee, MN United States

Lakeview Hospital

Stillwater, MN United States

Ridgeview Medical Center

Waconia, MN United States

Rice Memorial Hospital

Willmar, MN United States

Minnesota Oncology Hematology PA-Woodbury

Woodbury, MN United States

Fairview Lakes Medical Center

Wyoming, MN United States

Gundersen Lutheran Medical Center

La Crosse, WI United States

Cancer Center of Western Wisconsin

New Richmond, WI United States

Kaiser Permanente-Franklin

Denver, CO United States

SCL Health Saint Joseph Hospital

Denver, CO United States

Good Samaritan Medical Center

Lafayette, CO United States

Kaiser Permanente-Rock Creek

Lafayette, CO United States

Kaiser Permanente-Lone Tree

Lone Tree, CO United States

Siteman Cancer Center at Saint Peters Hospital

Saint Peters, MO United States

Good Samaritan Regional Health Center

Mount Vernon, IL United States

Cox Cancer Center Branson

Branson, MO United States

Capital Region Southwest Campus

Jefferson City, MO United States

Freeman Health System

Joplin, MO United States

Mercy Hospital Joplin

Joplin, MO United States

Delbert Day Cancer Institute at PCRMC

Rolla, MO United States

Heartland Regional Medical Center

Saint Joseph, MO United States

Mercy Hospital Saint Louis

Saint Louis, MO United States

Mercy Hospital Springfield

Springfield, MO United States

CoxHealth South Hospital

Springfield, MO United States

Mercy Hospital Washington

Washington, MO United States

Mercy Hospital Oklahoma City

Oklahoma City, OK United States

Covenant Medical Center-Lakeside

Lubbock, TX United States

Harold Alfond Center for Cancer Care

Augusta, ME United States

Waldo County General Hospital

Belfast, ME United States

Penobscot Bay Medical Center

Rockport, ME United States

Weisberg Cancer Treatment Center

Farmington Hills, MI United States

Moffitt Cancer Center

Tampa, FL United States

Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, ID United States

Walter Knox Memorial Hospital

Emmett, ID United States

Idaho Urologic Institute-Meridian

Meridian, ID United States

Saint Alphonsus Medical Center-Nampa

Nampa, ID United States

Sidney and Lois Eskenazi Hospital

Indianapolis, IN United States

Saint Joseph Mercy Hospital

Ann Arbor, MI United States

Saint Joseph Mercy Brighton

Brighton, MI United States

Saint Joseph Mercy Canton

Canton, MI United States

Caro Cancer Center

Caro, MI United States

Saint Joseph Mercy Chelsea

Chelsea, MI United States

Hematology Oncology Consultants-Clarkston

Clarkston, MI United States

Newland Medical Associates-Clarkston

Clarkston, MI United States

Great Lakes Cancer Management Specialists-Doctors Park

East China Township, MI United States

Genesee Hematology Oncology PC

Flint, MI United States

Genesys Hurley Cancer Institute

Flint, MI United States

Hurley Medical Center

Flint, MI United States

Lymphoma Clinic of Michigan

Grosse Pointe Woods, MI United States

Michigan Breast Specialists-Grosse Pointe Woods

Grosse Pointe Woods, MI United States

Sparrow Hospital

Lansing, MI United States

Hope Cancer Clinic

Livonia, MI United States

Saint Mary Mercy Hospital

Livonia, MI United States

21st Century Oncology-Pontiac

Pontiac, MI United States

Hope Cancer Center

Pontiac, MI United States

Newland Medical Associates-Pontiac

Pontiac, MI United States

Saint Joseph Mercy Oakland

Pontiac, MI United States

Saint Mary's of Michigan

Saginaw, MI United States

Bhadresh Nayak MD PC-Sterling Heights

Sterling Heights, MI United States

Saint Joseph Health System-Tawas City

Tawas City, MI United States

Advanced Breast Care Center PLLC

Warren, MI United States

Macomb Hematology Oncology PC

Warren, MI United States

Michigan Breast Specialists-Warren

Warren, MI United States

Saint John Macomb-Oakland Hospital

Warren, MI United States

Huron Gastroenterology PC

Ypsilanti, MI United States

IHA Hematology Oncology Consultants-Ann Arbor

Ypsilanti, MI United States

Saint Alphonsus Medical Center-Baker City

Baker City, OR United States

Saint Alphonsus Medical Center-Ontario

Ontario, OR United States

Lehigh Valley Hospital-Cedar Crest

Allentown, PA United States

Lehigh Valley Hospital - Muhlenberg

Bethlehem, PA United States

Pocono Medical Center

East Stroudsburg, PA United States

Lehigh Valley Hospital-Hazleton

Hazleton, PA United States

John B Amos Cancer Center

Columbus, GA United States

Saint Charles Health System-Redmond

Redmond, OR United States

PeaceHealth United General Medical Center

Sedro-Woolley, WA United States

Morristown Medical Center

Morristown, NJ United States

Overlook Hospital

Summit, NJ United States

University of Pennsylvania/Abramson Cancer Center

Philadelphia, PA United States

Loyola University Medical Center

Maywood, IL United States

Central Care Cancer Center - Garden City

Garden City, KS United States

Central Care Cancer Center - Great Bend

Great Bend, KS United States

Minimally Invasive Surgery Hospital

Lenexa, KS United States

Menorah Medical Center

Overland Park, KS United States

Central Care Cancer Center - Bolivar

Bolivar, MO United States

Centerpoint Medical Center LLC

Independence, MO United States

Research Medical Center

Kansas City, MO United States

Rush - Copley Medical Center

Aurora, IL United States

Carle on Vermilion

Danville, IL United States

Carle Physician Group-Effingham

Effingham, IL United States

Carle Physician Group-Mattoon/Charleston

Mattoon, IL United States

Carle Cancer Center

Urbana, IL United States

The Carle Foundation Hospital

Urbana, IL United States

Rush-Copley Healthcare Center

Yorkville, IL United States

Essentia Health Hibbing Clinic

Hibbing, MN United States

Welch Cancer Center

Sheridan, WY United States

Kaiser Permanente Downtown Commons

Sacramento, CA United States

East Carolina University

Greenville, NC United States

Stanford Cancer Institute Palo Alto

Palo Alto, CA United States

Stanford Cancer Center South Bay

San Jose, CA United States

Beebe Medical Center

Lewes, DE United States

Helen F Graham Cancer Center

Newark, DE United States

Regional Hematology and Oncology PA

Newark, DE United States

Beebe Health Campus

Rehoboth Beach, DE United States

Nanticoke Memorial Hospital

Seaford, DE United States

Trinity Regional Medical Center

Fort Dodge, IA United States

Southwest Illinois Health Services LLP

Swansea, IL United States

Parkview Hospital Randallia

Fort Wayne, IN United States

Essentia Health - Deer River Clinic

Deer River, MN United States

Essentia Health Saint Mary's - Detroit Lakes Clinic

Detroit Lakes, MN United States

Essentia Health - Fosston

Fosston, MN United States

Essentia Health - Park Rapids

Park Rapids, MN United States

Essentia Health Sandstone

Sandstone, MN United States

New Mexico Oncology Hematology Consultants

Albuquerque, NM United States

Essentia Health - Jamestown Clinic

Jamestown, ND United States

Ashland Memorial Medical Center

Ashland, WI United States

Fremont - Rideout Cancer Center

Marysville, CA United States

Hines Veterans Administration Hospital

Hines, IL United States

Sanford Thief River Falls Medical Center

Thief River Falls, MN United States

Sanford South University Medical Center

Fargo, ND United States

Saint John's Hospital - Healtheast

Maplewood, MN United States

Sanford Cancer Center Worthington

Worthington, MN United States

Veteran's Administration Medical Center

Little Rock, AR United States

Lawrence Memorial Hospital

Lawrence, KS United States

Cancer Center of Kansas - Wichita

Wichita, KS United States

Via Christi Regional Medical Center

Wichita, KS United States

Wesley Medical Center

Wichita, KS United States

Ascension Saint John Hospital

Detroit, MI United States

Abington Memorial Hospital

Abington, PA United States

Mercy Medical Center

Springfield, MA United States

Green Bay Oncology - Escanaba

Escanaba, MI United States

Holy Family Memorial Hospital

Manitowoc, WI United States

Green Bay Oncology - Oconto Falls

Oconto Falls, WI United States

HSHS Saint Nicholas Hospital

Sheboygan, WI United States

University of Colorado Hospital

Aurora, CO United States

Poudre Valley Hospital

Fort Collins, CO United States

Monticello Cancer Center

Monticello, MN United States

Rocky Mountain Cancer Centers-Aurora

Aurora, CO United States

Boulder Community Hospital

Boulder, CO United States

Rocky Mountain Cancer Centers-Boulder

Boulder, CO United States

Denver Health Medical Center

Denver, CO United States

National Jewish Health-Main Campus

Denver, CO United States

The Women's Imaging Center

Denver, CO United States

Colorado Blood Cancer Institute

Denver, CO United States

Rocky Mountain Cancer Centers-Midtown

Denver, CO United States

Rocky Mountain Cancer Centers-Rose

Denver, CO United States

Western Surgical Care

Denver, CO United States

Swedish Medical Center

Englewood, CO United States

Saint Mary's Hospital and Regional Medical Center

Grand Junction, CO United States

North Colorado Medical Center

Greeley, CO United States

Rocky Mountain Cancer Centers-Littleton

Littleton, CO United States

Rocky Mountain Cancer Centers-Sky Ridge

Lone Tree, CO United States

McKee Medical Center

Loveland, CO United States

SCL Health Lutheran Medical Center

Wheat Ridge, CO United States

Mid-Michigan Medical Center - Midland

Midland, MI United States

Saint Vincent Healthcare

Billings, MT United States

Saint Vincent Frontier Cancer Center

Billings, MT United States

Dickstein Cancer Treatment Center

White Plains, NY United States

Cheyenne Regional Medical Center-West

Cheyenne, WY United States

Baystate Medical Center

Springfield, MA United States

Recruitment Status: Closed


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