Mild Dementia/Alzheimer's Disease

  • sponsor
    Actinogen Medical
Updated on 25 March 2021


Mild Dementia/Alzheimer's Disease


Northern California Research is enrolling participants for a Mild Dementia/Alzheimer's Disease study. The purpose of this study is to see if daily doses of a study medication will improve the symptoms of mild dementia due to Alzheimer's disease. This study medication has been designed to change the cortisol levels in the brain. Cortisol is a naturally occurring hormone in your body. It is believed that reducing the level of cortisol will be a benefit in the treatment of Alzheimer's disease. This will be assessed by completing a series of assessments where you will be asked questions by the study staff and you will be asked to write down or verbally say the answers.

The design of the study is double-blind, randomized and placebo controlled. A "double blind" study means that the study doctor and the participants who take part won't know which group is administered the study medication and which group is administered placebo. You will not have to stop taking any medications you are currently taking for your cognitive symptoms such as memantine or donepezil; however, you must be on a stable dose or 3 months.

Clinical Study IdentifierTX152629
SponsorActinogen Medical
Last Modified on25 March 2021


Yes No Not Sure

Inclusion Criteria

Male and Females 50 years or older
Must be willing and able to comply with the requirements of the study
Have a consenting study partner who spends an average of 10 hours/week in contact with the participant and would be able to accompany the participant to all study visits

Exclusion Criteria

Have other neurological disease such as Parkinson’s disease, Huntington’s disease, normal pressure hydrocephalus, brain tumor
Has had a stroke within the last year
A diagnosis of a psychiatric disorder. This includes but is not limited to schizophrenia, schizoaffective disorder, bipolar affective disorder, alcohol dependence syndrome or major depressive disorder
Inability to communicate well with the investigator, poor mental development or impaired cerebral function
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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