Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST) (Alliance A151216)

Updated on 3 December 2020
lung cancer
lung carcinoma


Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST) (Alliance A151216)


Alchemist includes several clinical trials. Their goal is to test new therapies for patients like you: those with early stage non-small cell lung cancer whose tumor can be surgically removed. Some of the ALCHEMIST trials are seeking patients with specific mutations, or changes, in their cancer tumors. These changes are relatively rare: they exist in about 10 percent or less of all tumors. If your tumor has these changes, you may be given a new type of medicine called “targeted therapy.” These medicines are developed to “target,” or attack the changes in your tumor and prevent the cancer from returning. If your tumor does not have a specific mutation or change to the gene, you may have an opportunity to enroll in another ALCHEMIST study and receive an “immunotherapy” medicine that may help your own immune system prevent the cancer from returning.

Condition Lung Cancer
Clinical Study IdentifierTX149717
Last Modified on3 December 2020


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Inclusion Criteria

ALCHEMIST includes several clinical trials. First we will test your tumor to see if it has a specific mutation or gene change. To do this, you must participate in the ALCHEMIST screening trial
In this trial, a portion of your tumor and a blood sample will be tested. If your tumor has one of the changes, then you may have the opportunity to receive the targeted therapy in one of the ALCHEMIST treatment trials. If your tumor does not have one of the changes, then you may have an opportunity to receive the immunotherapy drug in another ALCHEMIST treatment trial
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How to participate?

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What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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