Study Seeking Patients with Schizophrenia

  • sponsor
Updated on 25 March 2021


Study Seeking Patients with Schizophrenia


A Phase II, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of the Efficacy and Safety of MK-8189 using Risperidone as an Active Control in Subjects Experiencing an Acute Episode of Schizophrenia

Condition Schizophrenia and Schizoaffective Disorders, Mental Disability, Psychosis
Clinical Study IdentifierTX148303
Last Modified on25 March 2021


Yes No Not Sure

Inclusion Criteria

Ages 18-50, inclusive
BMI 18.5-40, inclusive
Diagnosed with Schizophrenia with the onset of the first episode at least one year but no more than 20 years prior to study entry
Currently experiencing an acute episode of schizophrenia with the onset less than or equal to 4 weeks prior to screening
Have previously responded to an antipsychotic medication other than Clozapine in a prior psychotic episode

Exclusion Criteria

Has participated in a research study in the past 6 months or more than one in the past year
Unwilling to allow audio/video recording of assessments
History of treatment resistance
Hepatitis that has been active in the past 6 months; HIV
Cardiovascular or Cerebrovascular disease
History of untreated narrow angle glaucoma
Has ever been diagnosed with epilepsy or had any seizure disorder beyond one childhood febrile seizure
History of neuroleptic malignant syndrome
Substance or Alcohol Use Disorder in the past 6 months
Positive UDS at screening; positive ETOH and/or THC may be allowed if they don’t meet criteria for abuse or dependence
Active suicidal ideation in the past 2 months or suicide attempt in the past 6 months
Committed an act of violence (assaultive behavior) within the past 2 years or is at risk for future assaultive behavior
History of significant multiple and/or severe allergies (food, drugs, latex) or has had an anaphylactic reaction or significant intolerability to prescription or non-prescription drugs or food
Allergy or sensitivity to Risperidone
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note