Biofilm Epidemiology and Mechanisms in Colon Cancer

  • sponsor
    National Cancer Institute / Johns Hopkins University
Updated on 23 November 2020


Biofilm Epidemiology and Mechanisms in Colon Cancer


This research is being done to learn more about why people get colon cancer. We are looking to identify specific bacteria in the colon that may be linked to the development of colon cancer. We will look for these bacteria in the stool and in the pieces of tissue obtained from the colon. We are also looking for certain signs in the stool, urine, mouth swish, blood and tissue, that show which people may harbor these bacteria and which could tell us how this disease progresses.

About 2000 people are expected to take part.

There is no direct benefit to you from being in this study.

If you take part in this study, you may help others in the future.

Condition Cancer Prevention, Colon Cancer
Clinical Study IdentifierTX146406
SponsorNational Cancer Institute / Johns Hopkins University
Last Modified on23 November 2020


Yes No Not Sure

Inclusion Criteria

The colonoscopy will be standard of care
If you agree to be in this study, we will require you to do the following things
If you are a female capable of having children, the study doctor will ask you some questions to see if you are pregnant
Complete a questionnaire about your socio demographic data, your own and your family’s health background and about your eating habits. This information will be kept private and will not be shared without your consent
Allow us to collect small samples from the lining of your colon at the time of your colonoscopy. As part of your standard clinical care, you need an exam of the inside of your colon with a flexible tool (colonoscope). The reasons for the exam and the risks of the test will be explained by your doctor. We will take an additional 1-12 tissue samples for research purposes. Taking the research biopsies will prolong the procedure by 3-5 minutes
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note