A randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the effect of secukinumab on aortic vascular inflammation and cardiometabolic biomarkers after 12 weeks of treatment, compared to placebo, and up to 52 weeks of treatment with secukinumab in adult subjects with moderate to severe chronic plaque-type psoriasis
We are studying an injectable medication, secukinumab, in the treatment of moderate to severe plaque psoriasis. Patients will undergo 3 FDG-PET/CT scans during the study to assess inflammation of the large vessels in the body and the effects of secukinumab on this inflammation. The trial lasts for 52 weeks. Initially patients will be expected to attend weekly appointments. After the first month, the appointments will occur every one to two months. Patients must be able to inject the medications themselves or have a family member or friend inject the medication for them.
Qualified participants will receive related medical examinations, study medication, and imaging studies at no cost, and may be eligible for compensation for their time and travel. Please call us for more information.
Condition | Psoriasis and Psoriatic Disorders |
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Clinical Study Identifier | TX144740 |
Last Modified on | 23 November 2020 |
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