A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Screening Step) Lung-MAP Study
Squamous cell lung cancers make up about one-fourth of non-small cell lung cancers. Various chemotherapy drugs have been shown to improve survival for patients with advanced squamous lung cancer. Most patients will be treated at first with cisplatin or carboplatin in combination with a second chemotherapy drug such as gemcitabine, paclitaxel, docetaxel, or vinorelbine. In addition, an immunotherapy drug called nivolumab was recently FDA approved for patients with squamous lung cancer who previously received chemotherapy.
The purpose of this study screening step is to test specific genes and proteins in your tumor sample. Based on the test results, you will be assigned to one of the treatment studies. We do not know how accurate this screening will be in matching your tumor type to a drug to treat your tumor. You may choose to not take part in the treatment study assigned to you. Before you decide to get treatment on the study, you will be given information about the treatment and you will be asked if you wish to take part in treatment on this research study.
Condition | Squamous cell carcinoma, Lung Cancer |
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Clinical Study Identifier | TX143690 |
Sponsor | SWOG |
Last Modified on | 23 November 2020 |
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