Treatment Resistant Depression Study

Updated on 8 November 2020


Treatment Resistant Depression Study


A randomized, double-blind, active-controlled, multicenter study in male and female adult subjects with TRD to assess the efficacy, safety, and tolerability of flexibly dosed intranasal esketamine plus a newly initiated oral antidepressant compared with a newly initiated oral antidepressant plus intranasal placebo

Condition Depression (Treatment-Resistant)
Clinical Study IdentifierTX142213
Last Modified on8 November 2020


Yes No Not Sure

Inclusion Criteria

Males and females 18-64 years old
Subject must meet the DSM-5 diagnostic criteria for single-episode MDD (duration must be 2 years) or recurrent MDD

Exclusion Criteria

MDD with psychosis, bipolar or related disorders
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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