CTOT14

  • STATUS
    Recruiting
Updated on 8 November 2020

Summary

CTOT14

Description

The main focus of this study is to develop blood and/or urine tests that will help to detect early signs of rejection in people who have had a liver transplant. Researchers will examine blood, urine, and tissue samples and try to identify markers for certain conditions such as rejection, response to therapy, and scarring of the liver. Additionally, researchers would like to identify biomarkers that can detect damage to the native kidneys before blood levels of creatinine rises. By studying gene expression, researchers hope to be able to diagnose these conditions earlier and improve liver survival.

Details
Clinical Study IdentifierTX137418
Last Modified on8 November 2020

Eligibility

Yes No Not Sure

Inclusion Criteria

Male and female, ≥ 18 years of age
Subjects undergoing primary deceased-donor or living donor liver transplantation
Subject must be able to understand and provide informed consent

Exclusion Criteria

Need for combined organ transplantation
Previous solid organ and/or islet cell transplantation
Infection with HIV
Inability or unwillingness of a participant to comply with study protocol
Any condition that, in the opinion of the investigator, would interfere with the participant's ability to comply with study requirements
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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