ALERTS (Angel Med): Implanted device designed to continuously monitor the electrocardiogram signals and detect shifts that could indicate of a blockage of a coronary artery

Updated on 8 November 2020


ALERTS (Angel Med): Implanted device designed to continuously monitor the electrocardiogram signals and detect shifts that could indicate of a blockage of a coronary artery


The implant device is designed to continuously monitor the electrocardiogram signal and detect ST shifts that could be indicative of a blockage of a coronary artery. If it detects such events, the Guardian System then alerts the patient to seek immediate medical attention by delivering vibratory, auditory and visual alerts.

Patient Inclusion Criteria: Adults sufficiently ill to warrant an isolated AVR with or without concomitant procedures such as CABG or another valve reconstruction. (The three remaing valves must be of native tissue). Likely survival - 1 year post-op)

Patient Exclusion Criteria:
Candidates will be excluded from the study if ANY of the following conditions apply: In the investigator’s opinion, subject lacks ability to respond appropriately to alarms, e.g., illiteracy, poor memory or cognitive function, dementia or other condition affecting memory function, etc.

There is known compromised tissue at the site of lead implantation in the apex of the right ventricle, e.g., prior infarct affecting the RV apex location.

A permanent pacemaker or ICD is already in place or the patient is indicated for ICD or pacemaker implantation based on the guidelines published by the American College of Cardiology as Class I and IIa recommendations. Class IIb recommendations are at the investigator’s discretion.

Subject cannot feel the IMD vibration when placed on top of the skin on the left pectoral side of the chest.

Condition Coronary Artery Disease
Clinical Study IdentifierTX135549
Last Modified on8 November 2020


How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact



Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note