Last updated on September 2019

Central Mechanisms that Regulate Glucose Metabolism in Humans


Brief description of study

Central Mechanisms that Regulate Glucose Metabolism in Humans

Detailed Study Description

Doctors at the center are seeking healthy volunteers, aged 21-60, to participate in a medical research study to better understand glucose metabolism and brain function.

Inclusion Criteria:

  • BP < 130/90 (+-2 meds)
  • BMI < 35
  • Normal screening labs (CBC, chemistry, lft's PT/PTT)
  • No CAD
  • No first degree relatives with history of CAD or MI (men < 45; women < 55)
  • Good IV access
  • No other medical problems with exception: HTN (on < or = 2 meds), hypercholesterolemia, and stable retinopathy
  • Non-smoker

Exclusion Criteria:

  • BP>130/90 (+- medications)
  • BMI > 35
  • Abnormal EKG
  • History of CAD or exertional chest pain
  • First degree relative with DIABETES, early CAD or MI
  • Medications for medical or psychiatric conditions including: dofetilide, fosphenytoin/phenytoin trichlormethiazide (any thiazide), chlorpromazine and warfarin
  • < 4 week history of participation in another drug trial

Clinical Study Identifier: TX134856

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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