Diagnosis of Aspirin Hypersensitivity by Measuring Arachidonic Acid Metabolites after Low Dose Aspirin Challenge
This is a research study of a new approach to diagnose aspirin allergy. Hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) is frequently reported by patients requiring aspirin (ASA) for coronary artery disease or NSAIDs for pain management. Even though clinical challenge with relatively high doses of aspirin carries a substantial risk of severe reactions in ASA-hypersensitive population (e.g., bronchospasm), it is used as a gold standard to confirm the diagnosis of ASA hypersensitivity (AH) [1]. A safer, more time and cost efficient test to diagnose ASA-hypersensitivity would be useful.
Inclusion criteria:
Exclusion criteria:
Condition | Drug Allergy |
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Clinical Study Identifier | TX134849 |
Last Modified on | 23 November 2020 |
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