Myelofibrosis

  • STATUS
    Recruiting
Updated on 8 November 2020

Summary

Myelofibrosis

Description

Study of the JAK Inhibitor INCB018424 tablet administered orally to subjects with primary myelofibrosis, post-polycythemia vera-myelofibrosis or post-essential thrombocythemia-myelofibrosis

Patient Inclusion Criteria:

  • 18 + years of age,
  • diagnosis of PMF or PPV-MF, either resistant or refractory to, intolerant of, or in the investigator's opinion not candidates for available therapy, must have a life expectancy of at least 6 months

Patient Exclusion Criteria:

  • Subjects with a life expectancy of less than 6 months, subjects in whom MF disease is well controlled with current therapy, females who are pregnant or currently breastfeeding, subjects with inadequate bone marrow, subjects with inadequate liver or renal function, subjects with cardiac disease, subject with currently uncontrolled or unstable angina

Details
Condition Myelofibrosis
Clinical Study IdentifierTX134737
Last Modified on8 November 2020

Eligibility

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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