Effect of Adaptive Servo Ventilation (ASV) on Survival and Hospital Admissions in Heart Failure

  • participants needed
  • sponsor
    Toronto Rehabilitation Institute
Updated on 21 June 2021
Maggie Szeto
Primary Contact
Tokyo Medical University Hospital (3.9 mi away) Contact
+52 other location
medical therapy
ejection fraction
heart failure
beta blockers
beta-adrenergic blocking agents
obstructive sleep apnea


Sleep Apnea (SA) is a disorder that causes pauses in breathing during sleep that expose the heart to oxygen deprivation. It is common in patients with heart failure (HF) where it is associated with increased risk of hospitalizations and death. It is not known however whether treating SA reduces these risks. This study is looking at whether a respiratory device known as Adaptive Servo Ventilation (ASV) can reduce the rate of cardiovascular hospitalizations and death in subjects with HF and SA. Study subjects will randomly receive either their regular medications OR their regular medications plus ASV. They will be followed for approximately 5 years and information relevant to their health will be collected and compared.

Condition Heart failure, Heart disease, Sleep apnea, Sleep Apnea Syndromes, Congestive Heart Failure, Cardiac Disease, cardiac failure, congestive heart disease
Treatment Adaptive Servo Ventilation
Clinical Study IdentifierNCT01128816
SponsorToronto Rehabilitation Institute
Last Modified on21 June 2021

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