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Last updated on November 2019

A Healthy Volunteer Pharmacokinetics (PK)/Pharmacodynamics (PD) Safety and Tolerability Study of Andexanet in Healthy Japanese and Caucasian Subjects

Brief description of study

"This is a single-center, randomized, double-blind, and placebo-controlled trial designed to:

  1. demonstrate the degree to which administered andexanet doses can reverse Factor Ten A (FXa)-inhibitor induced anticoagulation; and 2) evaluate the safety and PK/PD of andexanet in healthy Japanese subjects taking direct FXa inhibitors at therapeutic doses."

Clinical Study Identifier: NCT03310021

Recruitment Status: Closed

Brief Description Eligibility Contact Research Team

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