Last updated on March 2019

Safety Tolerability Pharmacokinetics and Pharmacodynamics of IONIS-MAPTRx in Patients With Mild Alzheimer's Disease


Brief description of study

The purpose is to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of IONIS-MAPTRx in patients with Mild Alzheimer's Disease

Detailed Study Description

Allocation: RandomizedEndpoint Classification: Safety Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Investigator) Primary Purpose: Treatment

Clinical Study Identifier: NCT03186989

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Anne Lithonius

Clinical Research Services Turku CRST
Turku, Finland
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Ionis Pharmaceuticals

Charite - Universitaetsmedizin Berlin Campus Mitte
Berlin, Germany
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Barbara Kaminski

St Josef Hospital
Bochum, Germany
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Ralf Bodenschatz

MVZ Mittweida Gbr
Mittweida, Germany
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Christine Von Arnim

Universittsklinikum Ulm
Ulm, Germany
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Peter P De Deyn

Faculty Medical Sciences UMCG Neurology
Groningen, Netherlands
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Anne Borjesson-Hanson

Karolinska University Hospital Huddinge
Stockholm, Sweden
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Richard Fitzgerald

Royal Liverpool University Hospital
Liverpool, United Kingdom
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Cath Mummery

University College London Hospitals NHS Foundation Trust
London, United Kingdom
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Daniel Blackburn

Sheffield Institute for Translational Neuroscience (SITraN)
Sheffield, United Kingdom
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Anja Schneider

Deutsches Zentrum f r Neurodegenerative Erkrankungen (DZNE)
Bonn, Germany
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Angela Genge

Montreal Neurological Hospital
Montréal, Canada
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Anne Borjesson-Hanson

Minnesmottagningen
Mölndal, Sweden
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Recruitment Status: Open


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