Last updated on June 2019

A Study of Talazoparib in Men With DNA Repair Defects and Metastatic Castration-Resistant Prostate Cancer


Brief description of study

The purpose of this international, phase 2, open-label, response rate study of talazoparib is to assess the efficacy and safety of talazoparib in men with DNA repair defects metastatic castration-resistant prostate cancer (CRPC) who previously received taxane-based chemotherapy and progressed on at least 1 novel hormonal agent (enzalutamide and/or abiraterone acetate/prednisone).

Clinical Study Identifier: NCT03148795

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Arizona Oncology

Phoenix, AZ United States
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South County Hematology/Oncology

Chula Vista, CA United States
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Sharp Rees-Steely

Chula Vista, CA United States
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City of Hope-Antelope Valley

Lancaster, CA United States
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Medical Oncology Associates-SD

San Diego, CA United States
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Sharp Memorial Hospital

San Diego, CA United States
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Sharp Rees-Stealy

San Diego, CA United States
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Emory University Hospital

Atlanta, GA United States
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Emory University

Atlanta, GA United States
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The Emory Clinic

Atlanta, GA United States
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Piedmont Cancer Institute, PC

Fayetteville, GA United States
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Barnes-Jewish Hospital

Saint Louis, MO United States
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Christian Hospital North East

Saint Louis, MO United States
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Siteman Cancer Center - St. Peters

Saint Peters, MO United States
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Carolinas Medical Center

Charlotte, NC United States
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Levine Cancer Institute

Charlotte, NC United States
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Carolinas Medical Center-Mercy

Charlotte, NC United States
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Carolina Urologic Research Center

Myrtle Beach, SC United States
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Swedish Cancer Institute

Seattle, WA United States
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Swedish Medical Center

Seattle, WA United States
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Clinical Trials Pharmacy

Darlinghurst, Australia
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Westmead Hospital

Northmead, Australia
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Westmead Hospital

Westmead, Australia
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Icon Cancer Care Wesley

Auchenflower, Australia
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River City Pharmacy

Auchenflower, Australia
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Ion Cancer Care

South Brisbane, Australia
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Box Hill Hospital

Box Hill, Australia
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Pharmacy Department

Heidelberg, Australia
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ICO-Site Paul Papin

Angers Cedex 02, France
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Institut Bergonie

Bordeaux cedex, France
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Hopital Civil

Strasbourg, France
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Hopital Foch

Suresnes, France
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Biorylis Talmont-Saint-Hilaire

Talmont-saint Hilaire, France
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Institut Gustave-Roussy

Villejuif Cedex, France
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Asan Medical Center

Seoul, Korea, Republic of
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Radboud UMC

Nijmegen, Netherlands
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Mount Vernon Hospital

Northwood, United Kingdom
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Addenbrookes Hospital

Cambridge, United Kingdom
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Central Pharmacy, Level 1

Cambridge, United Kingdom
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Recruitment Status: Open


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