Last updated on February 2019

A 24-Month Study to Evaluate the Efficacy and Safety of E2609 in Subjects With Early Alzheimer's Disease_


Brief description of study

The name of this trial is MissionAD2. This 24-month treatment, multicenter, double-blind, placebo-controlled, parallel group, Phase 3 study in participants with Early Alzheimer's Disease (EAD) including mild cognitive impairment (MCI) due to Alzheimer's Disease (AD)/Prodromal AD and the early stages of mild AD will be conducted to evaluate the efficacy and safety of elenbecestat (proposed international nonproprietary name [pINN]) (E2609).

Clinical Study Identifier: NCT03036280

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Facility #1

Gilbert, AZ United States
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Facility #1

Phoenix, AZ United States
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Facility #2

Phoenix, AZ United States
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Phoenix, AZ United States
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Bellflower, CA United States
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Glendale, CA United States
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Irvine, CA United States
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La Jolla, CA United States
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Laguna Hills, CA United States
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Lomita, CA United States
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Long Beach, CA United States
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Los Angeles, CA United States
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Oceanside, CA United States
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Riverside, CA United States
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Santa Ana, CA United States
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Santa Ana, CA United States
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Santa Monica, CA United States
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Walnut Creek, CA United States
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New Haven, CT United States
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New London, CT United States
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Stamford, CT United States
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Aventura, FL United States
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Bradenton, FL United States
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Doral, FL United States
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Hialeah, FL United States
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Jacksonville, FL United States
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Jacksonville, FL United States
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Lake Worth, FL United States
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Maitland, FL United States
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Melbourne, FL United States
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Miami Lakes, FL United States
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Miami Springs, FL United States
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Facility #10

Miami, FL United States
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Miami, FL United States
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Facility #7

Miami, FL United States
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Miami, FL United States
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Facility #6

Miami, FL United States
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Miami, FL United States
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Facility #3

Miami, FL United States
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Miami, FL United States
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Facility #8

Miami, FL United States
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Miami, FL United States
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North Miami, FL United States
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Ocala, FL United States
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Orange City, FL United States
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Orlando, FL United States
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Ormond Beach, FL United States
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Palmetto Bay, FL United States
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Pembroke Pines, FL United States
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Pinellas Park, FL United States
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Saint Petersburg, FL United States
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West Palm Beach, FL United States
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Decatur, GA United States
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Chicago, IL United States
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Elk Grove Village, IL United States
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Schaumburg, IL United States
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Wichita, KS United States
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Baton Rouge, LA United States
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Burlington, MA United States
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Newton, MA United States
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Plymouth, MA United States
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Springfield, MA United States
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Hattiesburg, MS United States
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Creve Coeur, MO United States
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Omaha, NE United States
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Las Vegas, NV United States
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Toms River, NJ United States
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Toms River, NJ United States
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Albany, NY United States
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Manhasset, NY United States
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Staten Island, NY United States
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Woodmere, NY United States
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Charlotte, NC United States
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Charlotte, NC United States
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Shaker Heights, OH United States
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Oklahoma City, OK United States
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Medford, OR United States
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Portland, OR United States
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Norristown, PA United States
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Plains, PA United States
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Whitehall, PA United States
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Knoxville, TN United States
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Memphis, TN United States
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Dallas, TX United States
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DeSoto, TX United States
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Greenville, TX United States
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Houston, TX United States
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Mansfield, TX United States
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West Jordan, UT United States
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Richmond, VA United States
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Richmond, VA United States
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Middleton, WI United States
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Chatham, ON Canada
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Toronto, ON Canada
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Toronto, ON Canada
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Gatineau, QC Canada
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Greenfield Park, QC Canada
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Sherbrooke, QC Canada
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Verdun, QC Canada
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Santiago, Chile
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Facility #2

Santiago, Chile
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Santiago, Chile
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Santiago, Chile
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Antofagasta, Chile
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Vina del Mar, Chile
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Zagreb, Croatia
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Zagreb, Croatia
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Zagreb, Croatia
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Zagreb, Croatia
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Zagreb, Croatia
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Hostivice, Czechia
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Ostrava- Poruba, Czechia
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Praha 10, Czechia
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Praha 6, Czechia
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Rychnov nad Kneznou, Czechia
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Ballerup, Denmark
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Aalborg, Denmark
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Copenhagen, Denmark
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Helsinki, Finland
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Kuopio, Finland
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Aix-en-Provence, France
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Limoges, France
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TOURS Cedex, France
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Villeurbanne, France
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Mannheim, Germany
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Muenchen, Germany
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Munchen, Germany
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Bad Homburg, Germany
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Schwerin, Germany
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Westerstede, Germany
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Siegen, Germany
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Mittweida, Germany
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Berlin, Germany
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Bochum, Germany
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Dusseldorf, Germany
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Freiburg, Germany
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Hamburg, Germany
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Budapest, Hungary
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Facility #2

Budapest, Hungary
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Komarom-Esztergom, Hungary
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Ramat Gan, Israel
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Jerusalem, Israel
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Tel-Aviv, Israel
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Zerifin, Israel
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Arcugnano, Italy
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Orbassano, Italy
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Facility #1

Pozzilli, Italy
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Eisai Trial Site 1

Katsushika-ku, Japan
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Eisai Trial Site 1

Shinagawa-ku, Japan
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Eisai Trial Site 2

Shinagawa-ku, Japan
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Facility #1

Seongnam, Korea, Republic of
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Facility #1

Gwangju-si, Korea, Republic of
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Facility #1

Incheon, Korea, Republic of
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Seoul, Korea, Republic of
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Seoul, Korea, Republic of
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Seoul, Korea, Republic of
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Seoul, Korea, Republic of
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Facility #5

Seoul, Korea, Republic of
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Facility #6

Seoul, Korea, Republic of
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Guadalajara, Mexico
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Monterrey, Mexico
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Monterrey, Mexico
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Monterrey, Mexico
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Facility #1

Mexico City, Mexico
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Katowice, Poland
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Bialystok, Poland
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Facility #1

Bydgoszcz, Poland
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Facility #1

Pruszcz Gdanski, Poland
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Warszawa, Poland
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Amadora, Portugal
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Braga, Portugal
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Coimbra, Portugal
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Matosinhos, Portugal
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Porto, Portugal
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Santa Maria da Feira, Portugal
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Torres Vedras, Portugal
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Singapore, Singapore
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Singapore, Singapore
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Svidnik, Slovakia
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Banska Bystrica, Slovakia
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Bratislava, Slovakia
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Bratislava, Slovakia
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Bratislava, Slovakia
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Dubnica nad Vahom, Slovakia
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Kosice, Slovakia
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Rimavska Sobota, Slovakia
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Roznava, Slovakia
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Pinelands, South Africa
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Johannesburg, South Africa
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Cape Town, South Africa
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Facility #1

George, South Africa
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Facility #2

Barcelona, Spain
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Facility #1

San Sebastian, Spain
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Barcelona, Spain
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Facility #3

Barcelona, Spain
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Facility #1

Salamanca, Spain
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Facility #1

Changhua City, Taiwan
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Facility #1

Changhua, Taiwan
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Facility #1

Kaohsiung City, Taiwan
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Kaohsiung City, Taiwan
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New Taipei City, Taiwan
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Taichung City, Taiwan
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Facility #2

Tainan City, Taiwan
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Facility #3

Taipei City, Taiwan
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Facility #1

Taoyuan City, Taiwan
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Facility #1

Little Rock, AR United States
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Palo Alto, CA United States
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Facility #2

Hialeah, FL United States
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Facility #1

Newnan, GA United States
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Facility #1

Glens Falls, NY United States
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Salt Lake City, UT United States
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Guangzhou, China
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Facility #2

Guangzhou, China
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Facility #5

Guangzhou, China
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Facility #4

Guangzhou, China
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Facility #3

Guangzhou, China
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Facility #1

Zhengzhou, China
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Facility #1

Changchun, China
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Shanghai, China
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Facility #3

Shanghai, China
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Facility #4

Shanghai, China
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Facility #2

Shanghai, China
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Facility #5

Shanghai, China
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Facility #1

Shenzhen, China
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Eisai Trial Site 1

Hirosaki-city, Japan
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Eisai Trial Site 1

Isezaki-city, Japan
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Eisai Trial Site 1

Maebashi city, Japan
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Eisai Trial Site 1

Kanazawa-shi, Japan
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Eisai Trial Site 1

Fujisawa-shi, Japan
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Eisai Trial Site 1

Kamakura-shi, Japan
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Eisai Trial Site 1

Kawasaki-shi, Japan
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Eisai Trial Site 1

Kasukabe City, Japan
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Eisai Trial Site 1

Koshigaya-shi, Japan
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Eisai Trial Site 2

Koshigaya-shi, Japan
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Eisai Trial Site 1

Saitama city, Japan
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Eisai Trial Site 1

Shizuoka-city, Japan
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Imaging Endpoints

Scottsdale, AZ United States
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Facility #1

Villefranche-sur-Saône, France
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Facility #1

Guimaräes, Portugal
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Recruitment Status: Open


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