Last updated on January 2019

Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure


Brief description of study

The purpose of this study is to evaluate the effect of dapagliflozin on the incidence of worsening heart failure or cardiovascular death in patients with chronic heart failure with reduced ejection fraction.

Detailed Study Description

This is an international, multicentre, parallel group, event-driven, randomized, double-blind, placebo-controlled study in patients with chronic heart failure with reduced ejection fraction (HFrEF), evaluating the effect of dapagliflozin versus placebo, given once daily in addition to background regional standard of care therapy, for the prevention of cardiovascular (CV) death or reduction of heart failure (HF) events.

Clinical Study Identifier: NCT03036124

Contact Investigators or Research Sites near you

Start Over

Research Site

Fairhope, AL United States

Research Site

Huntsville, AL United States

Research Site

Mobile, AL United States

Research Site

Sheffield, AL United States

Research Site

Bakersfield, CA United States

Research Site

Beverly Hills, CA United States

Research Site

Los Angeles, CA United States

Research Site

Oceanside, CA United States

Research Site

Palm Springs, CA United States

Research Site

San Francisco, CA United States

Research Site

Torrance, CA United States

Research Site

Boynton Beach, FL United States

Research Site

Jacksonville, FL United States

Research Site

Miami, FL United States

Research Site

Naples, FL United States

Research Site

New Smyrna Beach, FL United States

Research Site

Pembroke Pines, FL United States

Research Site

Port Charlotte, FL United States

Research Site

Saint Augustine, FL United States

Research Site

Wellington, FL United States

Research Site

Atlanta, GA United States

Research Site

Cumming, GA United States

Research Site

Chicago, IL United States

Research Site

Hazel Crest, IL United States

Research Site

Peoria, IL United States

Research Site

Louisville, KY United States

Research Site

Alexandria, LA United States

Research Site

New Orleans, LA United States

Research Site

Bangor, ME United States

Research Site

Portland, ME United States

Research Site

Baltimore, MD United States

Research Site

Columbia, MD United States

Research Site

Boston, MA United States

Research Site

Haverhill, MA United States

Research Site

Natick, MA United States

Research Site

Detroit, MI United States

Research Site

Flint, MI United States

Research Site

Minneapolis, MN United States

Research Site

Tupelo, MS United States

Research Site

Kansas City, MO United States

Research Site

Saint Louis, MO United States

Research Site

Great Falls, MT United States

Research Site

Kalispell, MT United States

Research Site

Omaha, NE United States

Research Site

Las Vegas, NV United States

Research Site

Bridgewater, NJ United States

Research Site

New Brunswick, NJ United States

Research Site

Somerset, NJ United States

Research Site

Albany, NY United States

Research Site

Buffalo, NY United States

Research Site

New York, NY United States

Research Site

Orchard Park, NY United States

Research Site

Poughkeepsie, NY United States

Research Site

Rosedale, NY United States

Research Site

Burlington, NC United States

Research Site

Cleveland, OH United States

Research Site

Columbus, OH United States

Research Site

Altoona, PA United States

Research Site

Philadelphia, PA United States

Research Site

Pittsburgh, PA United States

Research Site

Rapid City, SD United States

Research Site

Knoxville, TN United States

Research Site

Memphis, TN United States

Research Site

Nashville, TN United States

Research Site

Tullahoma, TN United States

Research Site

Beaumont, TX United States

Research Site

Dallas, TX United States

Research Site

Fort Sam Houston, TX United States

Research Site

Houston, TX United States

Research Site

Kingwood, TX United States

Research Site

Tyler, TX United States

Research Site

Layton, UT United States

Research Site

Richmond, VA United States

Research Site

Everett, WA United States

Research Site

Seattle, WA United States

Research Site

Buenos Aires, Argentina

Research Site

Caba, Argentina

Research Site

Ciudad Autonoma Buenos Aires, Argentina

Research Site

Ciudad Autonoma de Buenos Aire, Argentina

Research Site

Ciudad Autonomade Buenos Aires, Argentina

Research Site

Ciudad de Buenos Aires, Argentina

Research Site

Cordoba, Argentina

Research Site

Corrientes, Argentina

Research Site

Esperanza, Argentina

Research Site

Mar del Plata, Argentina

Research Site

Quilmes, Argentina

Research Site

Rosario, Argentina

Research Site

San Luis, Argentina

Research Site

San Martin, Argentina

Research Site

San Miguel de Tucuman, Argentina

Research Site

Santa Fe, Argentina

Research Site

Vicente Lopez, Argentina

Research Site

Belo Horizonte, Brazil

Research Site

Brasilia, Brazil

Research Site

Brasillia, Brazil

Research Site

Campina Grande do Sul, Brazil

Research Site

Campinas, Brazil

Research Site

Campo Grande, Brazil

Research Site

Curitiba, Brazil

Research Site

Marilia, Brazil

Research Site

Pelotas, Brazil

Research Site

Porto Alegre, Brazil

Research Site

Rio de Janeiro, Brazil

Research Site

Sao Paulo, Brazil

Research Site

Uberlandia, Brazil

Research Site

Votuporanga, Brazil

Research Site

Blagoevgrad, Bulgaria

Research Site

Dimitrovgrad, Bulgaria

Research Site

Haskovo, Bulgaria

Research Site

Kyustendil, Bulgaria

Research Site

Lom, Bulgaria

Research Site

Pleven, Bulgaria

Research Site

Plovdiv, Bulgaria

Research Site

Sofia, Bulgaria

Research Site

Calgary, AB Canada

Research Site

New Westminster, BC Canada

Research Site

North Vancouver, BC Canada

Research Site

Surrey, BC Canada

Research Site

Brampton, ON Canada

Research Site

Cambridge, ON Canada

Research Site

Hamilton, ON Canada

Research Site

London, ON Canada

Research Site

North York, ON Canada

Research Site

Oshawa, ON Canada

Research Site

Peterborough, ON Canada

Research Site

Scarborough, ON Canada

Research Site

Toronto, ON Canada

Research Site

Waterloo, ON Canada

Research Site

York, ON Canada

Research Site

Greenfield Park, QC Canada

Research Site

Montreal, QC Canada

Research Site

Rimouski, QC Canada

Research Site

Saint-Charles-Borromee, QC Canada

Research Site

Saint-Jerome, QC Canada

Research Site

Terrebonne, QC Canada

Research Site

Quebec, QC Canada

Research Site

Beijing, China

Research Site

Bengbu, China

Research Site

Changsha, China

Research Site

Chengdu, China

Research Site

Chifeng, China

Research Site

Chongqing, China

Research Site

Dalian, China

Research Site

Daqing, China

Research Site

Guangzhou, China

Research Site

Jilin, China

Research Site

Nanchang, China

Research Site

Nanjing, China

Research Site

Ningbo, China

Research Site

Pingxiang, China

Research Site

Shanghai, China

Research Site

Shenyang, China

Research Site

Shenzhen, China

Research Site

Taiyuan, China

Research Site

Tianjin, China

Research Site

Wuhan, China

Research Site

Xian, China

Research Site

Xuzhou, China

Research Site

Zhuhai, China

Research Site

Benesov, Czechia

Research Site

Brno, Czechia

Research Site

Kolin, Czechia

Research Site

Louny, Czechia

Research Site

Ostrava-Dubina, Czechia

Research Site

Plzen, Czechia

Research Site

Praha 2, Czechia

Research Site

Praha 4, Czechia

Research Site

Praha 5, Czechia

Research Site

Praha, Czechia

Research Site

Pribram, Czechia

Research Site

Trebic, Czechia

Research Site

Hellerup, Denmark

Research Site

Herlev, Denmark

Research Site

Hvidovre, Denmark

Research Site

Odense C, Denmark

Research Site

Svendborg, Denmark

Research Site

Bad Oeynhausen, Germany

Research Site

Berlin, Germany

Research Site

Dresden, Germany

Research Site

Essen, Germany

Research Site

Hamburg, Germany

Research Site

Homburg, Germany

Research Site

Kassel, Germany

Research Site

Leipzig, Germany

Research Site

Mainz, Germany

Research Site

Markkleeberg, Germany

Research Site

Papenburg, Germany

Research Site

Stuttgart, Germany

Research Site

Wermsdorf, Germany

Research Site

Budapest, Hungary

Research Site

Szentes, Hungary

Research Site

Zalaegerszeg, Hungary

Research Site

Ahmedabad, India

Research Site

Aurangabad, India

Research Site

Bangalore, India

Research Site

Belagavi, India

Research Site

Ernakulam, India

Research Site

Guntur, India

Research Site

Gurgaon, India

Research Site

Kanpur, India

Research Site

Karamsad, India

Research Site

Kolkata, India

Research Site

Maharashtra, India

Research Site

Mangalore, India

Research Site

Nadiad, India

Research Site

Nagpur, India

Research Site

New Delhi, India

Research Site

Pune, India

Research Site

Vijayawada, India

Research Site

Adachi-ku, Japan

Research Site

Aki-gun,, Japan

Research Site

Azumino-shi, Japan

Research Site

Beppu-shi, Japan

Research Site

Bunkyo-ku, Japan

Research Site

Chikushino-shi, Japan

Research Site

Chuo-ku, Japan

Research Site

Fujisawa-shi, Japan

Research Site

Fukuoka-shi, Japan

Research Site

Hachioji-shi, Japan

Research Site

Hamamatsu-shi, Japan

Research Site

Himeji-shi, Japan

Research Site

Hiratsuka-shi, Japan

Research Site

Hitachinaka-shi, Japan

Research Site

Iizuka-shi, Japan

Research Site

Itabashi-ku, Japan

Research Site

Iwakuni-shi, Japan

Research Site

Kagoshima-shi, Japan

Research Site

Kakamigahara-shi, Japan

Research Site

Kanoya-shi, Japan

Research Site

Kasama-shi, Japan

Research Site

Kishiwada-shi, Japan

Research Site

Kitakyusyu-shi, Japan

Research Site

Kumamoto-shi, Japan

Research Site

Kure-shi, Japan

Research Site

Kusatsu-shi, Japan

Research Site

Kyoto-shi, Japan

Research Site

Matsudo-shi, Japan

Research Site

Matsumoto-shi, Japan

Research Site

Matsuyama-shi, Japan

Research Site

Meguro-ku, Japan

Research Site

Mito-shi, Japan

Research Site

Miura-gun, Japan

Research Site

Nagasaki-shi, Japan

Research Site

Nagoya-shi, Japan

Research Site

Naha, Japan

Research Site

Nishinomiya-shi, Japan

Research Site

Okayama-shi, Japan

Research Site

Osaka-shi, Japan

Research Site

Sagamihara-shi, Japan

Research Site

Sakai-shi,Kita-ku, Japan

Research Site

Sakaide-shi, Japan

Research Site

Sanyoonoda-shi, Japan

Research Site

Sayama-shi, Japan

Research Site

Sendai-shi, Japan

Research Site

Shimonoseki-shi, Japan

Research Site

Shinjuku-ku, Japan

Research Site

Suita-shi, Japan

Research Site

Suwa-shi, Japan

Research Site

Tachikawa-shi, Japan

Research Site

Takamatsu-shi, Japan

Research Site

Takasaki-shi, Japan

Research Site

Toride-shi, Japan

Research Site

Tsuchiura-shi, Japan

Research Site

Tsukuba-shi, Japan

Research Site

Ueda-shi, Japan

Research Site

Uruma-shi, Japan

Research Site

Wakayama-shi, Japan

Research Site

Wako-shi, Japan

Research Site

Yokohama-shi, Japan

Research Site

Apeldoorn, Netherlands

Research Site

Den Bosch, Netherlands

Research Site

Den Haag, Netherlands

Research Site

Gouda, Netherlands

Research Site

Groningen, Netherlands

Research Site

Nijmegen, Netherlands

Research Site

Rotterdam, Netherlands

Research Site

Sneek, Netherlands

Research Site

Veldhoven, Netherlands

Research Site

Bochnia, Poland

Research Site

Gdynia, Poland

Research Site

Washington, WA United States

Research Site

Lake Worth, FL United States

Research Site

Bay City, MI United States

Research Site

Bronx, NY United States

Research Site

Cortlandt Manor, NY United States

Research Site

Abbotsford, BC Canada

Research Site

Oakville, ON Canada

Research Site

Port Perry, ON Canada

Research Site

Baotou, China

Research Site

Alexander City, AL United States

Research Site

Stockton, CA United States

Research Site

Wilmington, DE United States

Research Site

Jerseyville, IL United States

Research Site

Chalmette, LA United States

Research Site

Duluth, MN United States

Research Site

Saint Paul, MN United States

Research Site

Grand Island, NE United States

Research Site

Lincoln, NE United States

Research Site

Falls Church, VA United States

Research Site

Moncton, NB Canada

Research Site

Newmarket, ON Canada

Research Site

Changchun, China

Research Site

Tucker, GA United States

Research Site

Arlington Heights, IL United States

Research Site

Langhorne, PA United States

Research Site

Katy, TX United States

Research Site

Saint John, NB Canada

Research Site

Yinchuan, China

Research Site

Lansing, MI United States

Research Site

Córdoba, Argentina

Research Site

Ramos Mejía, Argentina

Research Site

San Nicolás, Argentina

Research Site

Goiânia, Brazil

Research Site

São José do Rio Preto, Brazil

Research Site

Vitória, Brazil

Research Site

Købehhavn Ø, Denmark

Research Site

Kecskemét, Hungary

Research Site

Mosonmagyaróvár, Hungary

Research Site

Székesfehérvár, Hungary

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


Receive Emails About New Clinical Trials!

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.