Last updated on April 2019

A Study of Napabucasin Plus Nab-Paclitaxel With Gemcitabine in Adult Patients With Metastatic Pancreatic Adenocarcinoma


Brief description of study

This is a randomized, open-label, multi-center, phase 3 study of napabucasin plus weekly nab-paclitaxel with gemcitabine versus weekly nab-paclitaxel with gemcitabine for adult patients with Metastatic Pancreatic Ductal Adenocarcinoma.

Clinical Study Identifier: NCT02993731

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Highlands Oncology Group

Fayetteville, AR United States

Comprehensive Blood and Cancer Center

Bakersfield, CA United States

Los Angeles Hematology Oncology Medical Group

Los Angeles, CA United States

Torrance Health Association DBA Torrance Memorial

Redondo Beach, CA United States

Pacific Hematology Oncology Associates

San Francisco, CA United States

Lakeland Regional Medical Center (LRMC)

Lakeland, FL United States

Mount Sinai Medical Center

Miami Beach, FL United States

UF Health Cancer Center - Orlando Health

Orlando, FL United States

Florida Cancer Specialists North

Saint Petersburg, FL United States

Florida Cancer Specialists East Region

Wellington, FL United States

Ingalls Cancer Research Center

Harvey, IL United States

Northwestern Medicine Regional Medical Group

Warrenville, IL United States

Parkview Physician Group (PPG)

Fort Wayne, IN United States

Indiana University - Melvin and Bren Simon Cancer

Indianapolis, IN United States

Cotton O'Neil Cancer Center

Topeka, KS United States

Metro MN Clinical Oncology Research Consortium

Saint Louis Park, MN United States

HCA Midwest Division (Kansas City)

Kansas City, MO United States

Washington University School of Medicine

Saint Louis, MO United States

St. Vincent Frontier Cancer Center

Billings, MT United States

Basset Medical Center

Cooperstown, NY United States

Clinical Research Alliance

Lake Success, NY United States

FirstHealth Outpatient Cancer Center

Pinehurst, NC United States

Kaiser Permanente - Westside Medical Office

Hillsboro, OR United States

OHSU Knight Cancer Institute

Portland, OR United States

Fox Chase Cancer Center (FCCC) - Philadelphia

Philadelphia, PA United States

Charleston Hematology Oncology Associates

Charleston, SC United States

Saint Francis Cancer Center

Greenville, SC United States

GHS Cancer Institute

Greenville, SC United States

Tennessee Oncology Chattanooga

Chattanooga, TN United States

University of Tennessee Medical Center

Knoxville, TN United States

SCRI - Tennessee Oncology

Nashville, TN United States

The Center for Cancer and Blood Disorders

Fort Worth, TX United States

Bon Secours Cancer Institute Medical Oncology

Midlothian, VA United States

Virginia Cancer Institute

Richmond, VA United States

The Everett Clinic

Everett, WA United States

Border Medical Oncology

East Albury, Australia

Macquarie University Hospital

Sydney, Australia

ICON Cancer Care

South Brisbane, Australia

Cabrini Hospital

Malvern, Australia

ULB Erasme

Bruxelles, Belgium

Centre Eugene Marquis

Rennes, France

Kanagawa Cancer Center

Yokohama, Japan

Shizuoka Cancer Center

Sunto, Japan

Tochigi Cancer Center

Utsunomiya, Japan

Seoul national University Bundang Hospital

Gyeonggi-do, Korea, Republic of

Chonnam National University Hwasun Hospital

Jeongnam, Korea, Republic of

Seoul National University Hospital

Seoul, Korea, Republic of

Severance Hospital

Seoul, Korea, Republic of

Asan Medical Center

Seoul, Korea, Republic of

Samsung Medical Center

Seoul, Korea, Republic of

Seoul St. Mary's Hospital

Seoul, Korea, Republic of

Korea University Guro Hospital

Seoul, Korea, Republic of

University Medical Center Utrecht

Utrecht, Netherlands

UAB Comprehensive Cancer Center

Birmingham, AL United States

Clearview Cancer Institute (CCI)

Huntsville, AL United States

Mayo clinic

Phoenix, AZ United States

St. Joseph Hospital of Orange

Orange, CA United States

UC Davis

Sacramento, CA United States

Kaiser Permanente - Vallejo Medical Center

Vallejo, CA United States

Helen F. Graham Cancer Center

Newark, DE United States

Georgetown University Medical Center (GUMC)

Washington, WA United States

Memorial Regional Hospital

Hollywood, FL United States

Mayo Clinic Cancer Center

Jacksonville, FL United States

Cancer Specialists of North Florida

Jacksonville, FL United States

University Cancer & Blood Center

Athens, GA United States

Columbus Regional Research Institute

Columbus, GA United States

Saint Alphonsus Health System

Boise, ID United States

Carle Cancer Center CCOP

Urbana, IL United States

Cancer Center of Kansas

Wichita, KS United States

Louisiana Hematology Oncology Associates (LHOA)

Baton Rouge, LA United States

Maine Center for Cancer Medicine - Scarborough

Scarborough, ME United States

Greater Baltimore Medical Center

Baltimore, MD United States

UMass Memorial Medical Center

Worcester, MA United States

Barbara Ann Karmanos Cancer Institute

Detroit, MI United States

St. Luke's Hospital of Duluth

Duluth, MN United States

Mayo Clinic

Rochester, MN United States

Jackson Oncology Associates

Jackson, MS United States

Saint Luke's Hospital

Kansas City, MO United States

Mercy Clinic - Cancer & Hematology

Springfield, MO United States

Nebraska Methodist Hospital

Omaha, NE United States

Englewood Hospital and Medical Center

Englewood, NJ United States

UNM Cancer Research and Treatment Center

Albuquerque, NM United States

Montefiore Cancer Center

Bronx, NY United States

North Shore Hematology Oncology Associates PC

East Setauket, NY United States

Hematology Oncology Associates of Central New York

East Syracuse, NY United States

University of Rochester Medical Center

Rochester, NY United States

Stony Brook University

Stony Brook, NY United States

Cone Health Cancer Center

Greensboro, NC United States

Toledo Clinic Cancer Centers

Toledo, OH United States

Mercy Clinic Oncology and Hematology - McAuley

Oklahoma City, OK United States

Avera Medical Group

Sioux Falls, SD United States

Green Bay Oncology, Ltd. - West Green Bay

Green Bay, WI United States

The Austin Hospital

Heidelberg, Australia

Sir Charles Gairdner Hospital

Nedlands, Australia

Prince of Wales Private Hospital

Randwick, Australia

The Tweed Hospital

Tweed Heads, Australia

Sydney Adventist Hospital

Wahroonga, Australia

Landeskrankenhaus Feldkirch

Rankweil, Austria

Antwerp University Hospital

Edegem, Belgium

UZ Ghent

Gent, Belgium

UZ Brussel

Jette, Belgium

UZ Leuven

Leuven, Belgium

CHU Dinant Godinne

Yvoir, Belgium

CHU-H tel Dieu

Nantes Cedex 1, France

Poitiers University Hospital

Poitiers, France

Clinique Saint Anne

Strasbourg, France

Hopital Civil de strasbourg

Strasbourg, France

Krankenhaus Nordwest

Frankfurt am main, Germany

SLK-Kliniken Heilbronn GmbH

Heilbronn, Germany

Fondazione Poliambulanza

Brescia, Italy

Ospedale degli Infermi

Faenza, Italy

AOU Mater Domini

Germaneto Catanzaro, Italy

Ospedale degli Infermi

Rimini, Italy

Shikoku Cancer Center

Matsuyama, Japan

Kyoto University Hospital

Sakyo-ku, Japan

Saitama Cancer Center

Kita Adachi-gun, Japan

Banner MD Anderson Cancer Center

Gilbert, AZ United States

Mayo Clinic

Phoenix, AZ United States

University of Southern California

Los Angeles, CA United States

Sylvester Comprehensive Cancer Center

Miami, FL United States

NorthShore University Health Systems

Evanston, IL United States

Norton Cancer Institute

Louisville, KY United States

San Juan Oncology Associates

Farmington, NM United States

Southeastern Medical Oncology Center

Goldsboro, NC United States

Wake Forest Baptist Hospital

Winston-Salem, NC United States

Cancer Center of Southwest Oklahoma

Lawton, OK United States

Allegheny General Hospital

Pittsburgh, PA United States

Medical University of South Carolina (MUSC)

Charleston, SC United States

Baylor College of Medicine

Houston, TX United States

Medical University Vienna

Vienna, Austria

Centre Hospitalier de St. Mary

Pointe-Claire, QC Canada

Cross Cancer Institute

Edmonton, Canada

Fakultni nemocnice Hradec Kralove

Hradec Kralove, Czechia

University Hospital Olomouc

Olomouc, Czechia

Hopital Edourard Herriot

Lyon Cedex 03, France

University Hospital Bonn

Bonn, Germany

Klinikum Chemnitz

Chemnitz, Germany

Medizinische Hochschule

Hannover, Germany

Universit tsmedizin Mannheim

Mannheim, Germany

AO SM Misericordia

Perugia, Italy

ASST Settelaghi

Varese, Italy

CHU de Liege

Liège, Belgium

Ciusssmcq

Trois-Rivières, QC Canada

Beijing Cancer Hospital

Beijing, China

Jilin Cancer Hospital

Changchun, China

Guangdong General Hospital

Guangzhou, China

Zhejiang Cancer Hospital

Hangzhou, China

Jiangsu Cancer Hospital

Nanjing, China

Huashan Hospital

Shanghai, China

Henan Cancer Hospital

Zhengzhou, China

Onkologicke oddeleni

Benešov, Czechia

Onkologick odd len

Zlín, Czechia

H pital Trousseau, CHRU de Tours

Chambray-lès-Tours, France

Institute de Cancerologie de Lorraine

Vandœuvre-lès-Nancy, France

Klinikum Bogenhausen

München, Germany

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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