Last updated on July 2019
Evaluation of Major Cardiovascular Events in Patients With or at High Risk for Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or Placebo
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
-
Conditions: Statin Adverse Reaction | Cardiovascular Disease
-
Age: Between 18 - 85 Years
-
Gender: Male or Female
Inclusion Criteria:
- Age between 18 and 85 years
- History of, or at high risk for, cardiovascular disease (CVD) including coronary artery disease, symptomatic peripheral arterial disease, cerebrovascular atherosclerotic disease, or at high risk for a cardiovascular event
- Patient reported history of statin intolerance (inability to tolerate 2 or more statins, one at a low dose)
- Men and nonpregnant, nonlactating women
- Fasting blood LDL-cholesterol 100 (2.6 mmol/L) at screening
Exclusion Criteria:
- Fasting blood triglycerides greater than 500 mg/dL (5.6 mmol/L) at screening
- Recent (within 90 days of screening) history of major cardiovascular events, transient ischemic attack (TIA), or unstable or symptomatic cardiac arrhythmia
- History of severe heart failure
- Uncontrolled hypertension or uncontrolled diabetes
