Last updated on January 2019

A 24-Month Study to Evaluate the Efficacy and Safety of E2609 in Subjects With Early Alzheimer's Disease


Brief description of study

The name of this trial is MissionAD1. This 24-month treatment, multicenter, double-blind, placebo-controlled, parallel group, Phase 3 study in participants with Early Alzheimer's Disease (EAD) including mild cognitive impairment (MCI) due to Alzheimer's Disease (AD)/Prodromal AD and the early stages of mild AD will be conducted to evaluate the efficacy and safety of elenbecestat (proposed international nonproprietary name [INN]) (E2609).

Clinical Study Identifier: NCT02956486

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Little Rock, AR United States
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Costa Mesa, CA United States
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Fullerton, CA United States
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Imperial, CA United States
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Irvine, CA United States
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National City, CA United States
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Oceanside, CA United States
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Oxnard, CA United States
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San Diego, CA United States
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San Marcos, CA United States
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Yorba Linda, CA United States
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Denver, CO United States
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Atlantis, FL United States
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Aventura, FL United States
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Boynton Beach, FL United States
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Brooksville, FL United States
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Coral Gables, FL United States
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Coral Gables, FL United States
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Deerfield Beach, FL United States
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Delray Beach, FL United States
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Doral, FL United States
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Hialeah, FL United States
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Lake Worth, FL United States
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Melbourne, FL United States
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Merritt Island, FL United States
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Miami, FL United States
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Miami, FL United States
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Miami, FL United States
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Miami, FL United States
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Miami, FL United States
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Miami, FL United States
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Miami, FL United States
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Miami, FL United States
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Miami, FL United States
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Miami, FL United States
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Orlando, FL United States
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Orlando, FL United States
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Orlando, FL United States
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Palm Beach Gardens, FL United States
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Port Charlotte, FL United States
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Tampa, FL United States
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Tampa, FL United States
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The Villages, FL United States
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Atlanta, GA United States
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Decatur, GA United States
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Suwanee, GA United States
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Meridian, ID United States
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Northbrook, IL United States
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Springfield, IL United States
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Wichita, KS United States
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Wichita, KS United States
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Boston, MA United States
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Farmington Hills, MI United States
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O'Fallon, MO United States
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Saint Louis, MO United States
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Saint Louis, MO United States
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Saint Louis, MO United States
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Saint Peters, MO United States
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Mount Arlington, NJ United States
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Princeton, NJ United States
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Springfield, NJ United States
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Toms River, NJ United States
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West Long Branch, NJ United States
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Amherst, NY United States
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Brooklyn, NY United States
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New York, NY United States
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Canton, OH United States
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Centerville, OH United States
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Cleveland, OH United States
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Dayton, OH United States
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Lakewood, OH United States
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Oklahoma City, OK United States
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Portland, OR United States
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Jenkintown, PA United States
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Media, PA United States
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Philadelphia, PA United States
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East Providence, RI United States
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East Providence, RI United States
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Lincoln, RI United States
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Providence, RI United States
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Port Royal, SC United States
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Cordova, TN United States
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Nashville, TN United States
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Nashville, TN United States
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Austin, TX United States
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Dallas, TX United States
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Houston, TX United States
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San Antonio, TX United States
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San Antonio, TX United States
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San Antonio, TX United States
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Salt Lake City, UT United States
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Bennington, VT United States
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Newport News, VA United States
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Richland, WA United States
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Madison, WI United States
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Caba, Argentina
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Caba, Argentina
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Caba, Argentina
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Caba, Argentina
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Cordoba, Argentina
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Rosario, Argentina
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Buenos Aires, Argentina
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Caba, Argentina
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Cordoba, Argentina
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Cordoba, Argentina
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Santa Fe, Argentina
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Darlinghurst, Australia
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Kanwal, Australia
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Macquarie Park, Australia
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Brisbane, Australia
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Geelong, Australia
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Heidelberg, Australia
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Malvern, Australia
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Melbourne, Australia
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Parkville, Australia
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Nedlands, Australia
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West Perth, Australia
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Melbourne, Australia
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Vienna, Austria
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Pleven, Bulgaria
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Plovdiv, Bulgaria
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Sofia, Bulgaria
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Sofia, Bulgaria
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Sofia, Bulgaria
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Sofia, Bulgaria
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Varna, Bulgaria
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Kelowna, BC Canada
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West Vancouver, BC Canada
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Kentville, NS Canada
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Ottawa, ON Canada
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Peterborough, ON Canada
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Montreal, QC Canada
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Sherbrooke, QC Canada
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Hradec Kralove, Czechia
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Kladno, Czechia
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Olomouc, Czechia
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Praha 10, Czechia
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Praha 6, Czechia
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Praha 6, Czechia
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Montpellier, France
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Bordeaux, France
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Bron Cedex, France
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Marseille Cedex 05, France
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Toulouse, France
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Gunzburg, Germany
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Munchen, Germany
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Neuburg, Germany
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Hoppegarten, Germany
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Oranienburg, Germany
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Frankfurt, Germany
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Magdeburg, Germany
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Leipzig, Germany
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Berlin, Germany
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Schwerin, Germany
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Wiesbaden, Germany
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Eisai Trial Site 1

Higashimorokatagun, Japan
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Facility #1

Bucheon-si, Korea, Republic of
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Seongnam, Korea, Republic of
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Busan, Korea, Republic of
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Incheon, Korea, Republic of
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Seoul, Korea, Republic of
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Seoul, Korea, Republic of
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Seoul, Korea, Republic of
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Seoul, Korea, Republic of
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Seoul, Korea, Republic of
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Facility #6

Seoul, Korea, Republic of
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Katowice, Poland
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Warszawa, Poland
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Campulung, Romania
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Bucharest, Romania
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Caracal, Romania
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Bucharest, Romania
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Bucharest, Romania
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Otopeni, Romania
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Belgrade, Serbia
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Kragujevac, Serbia
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Kragujevac, Serbia
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Novi Knezevac, Serbia
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Sant Cugat Del Valles, Spain
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Donostia/San Sebastian, Spain
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Palma de Mallorca, Spain
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El Palmar, Spain
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Barcelona, Spain
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Barcelona, Spain
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Valencia, Spain
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Valencia, Spain
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Molndal, Sweden
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Stockholm, Sweden
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Cambridge, United Kingdom
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Chester, United Kingdom
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Plymouth, United Kingdom
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Bournemouth, United Kingdom
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Crowborough, United Kingdom
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Manchester, United Kingdom
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Southampton, United Kingdom
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Glasgow, United Kingdom
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Blackpool, United Kingdom
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Preston, United Kingdom
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London, United Kingdom
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Bath, United Kingdom
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Northampton, United Kingdom
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Belfast, United Kingdom
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Oxford, United Kingdom
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Aberdeen, United Kingdom
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Sheffield, United Kingdom
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Leatherhead, United Kingdom
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Dundee, United Kingdom
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Birmingham, United Kingdom
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Swindon, United Kingdom
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Edinburgh, United Kingdom
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Glasgow, United Kingdom
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Guildford, United Kingdom
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London, United Kingdom
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London, United Kingdom
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London, United Kingdom
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Penarth, United Kingdom
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Chandler, AZ United States
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Colton, CA United States
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Oceanside, CA United States
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Panorama City, CA United States
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Port Orange, FL United States
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Spring Hill, FL United States
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Columbus, GA United States
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Chesterfield, MO United States
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Westerville, OH United States
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Facility #1

Hampton, VA United States
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Facility #1

Ciudad Autonoma de Buenos Aires, Argentina
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Facility #3

Ciudad Autonoma de Buenos Aires, Argentina
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Facility #2

Ciudad Autonoma de Buenos Aires, Argentina
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Facility #1

Tumbi Umbi, Australia
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Caulfield, Australia
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Facility #1

Kamloops, BC Canada
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Halifax, NS Canada
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Facility #2

Berlin, Germany
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Facility #1

Homburg/Saar, Germany
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Eisai Trial Site 1

Fujisawa-shi, Japan
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Eisai Trial Site 1

Nishisonogi-gun, Japan
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Eisai Trial Site 1

Kurashiki-shi, Japan
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Eisai Trial Site 2

Kurashiki-shi, Japan
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Facility #1

Nürnberg, Germany
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Recruitment Status: Open


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