Last updated on February 2019

Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100)


Brief description of study

This is a phase 3 randomized, placebo controlled study to evaluate the safety and anti-tumor activity of Avelumab in combination with standard of care chemoradiation (SoC CRT) versus SoC CRT alone in front-line treatment of patients with locally advanced head and neck cancer.

Clinical Study Identifier: NCT02952586

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Highlands Oncology Group

Fayetteville, AR United States
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Highlands Oncology Group

Rogers, AR United States
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St. Jude Medical Center

Fullerton, CA United States
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UC Irvine Medical Center

Orange, CA United States
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Anschutz Cancer Pavilion

Aurora, CO United States
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Primary Healthcare Associates

Flossmoor, IL United States
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Ingalls Memorial Hospital

Harvey, IL United States
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Primary Healthcare Associates

Tinley Park, IL United States
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University Medical Center, Inc.

Louisville, KY United States
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Highlands Cancer Center

Prestonsburg, KY United States
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Karmanos Cancer Institute

Detroit, MI United States
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Henry Ford Hospital

Detroit, MI United States
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Karmanos Cancer Institute

Farmington Hills, MI United States
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Barnes-Jewish Hospital

Saint Louis, MO United States
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Bellevue Hospital Center

New York, NY United States
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NYU Langone Medical Center

New York, NY United States
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Stony Brook University

Stony Brook, NY United States
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Stony Brook Cancer Center

Stony Brook, NY United States
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Wake Forest Baptist Health

Winston-Salem, NC United States
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OU Medical Center

Oklahoma City, OK United States
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Stephenson Cancer Center

Oklahoma City, OK United States
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UPMC Hillman Cancer Center

Pittsburgh, PA United States
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MUSC- Rutledge Tower

Charleston, SC United States
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MUSC- Ashley River Tower

Charleston, SC United States
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MUSC- Radiation Oncology

Charleston, SC United States
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MUSC- University Hospital

Charleston, SC United States
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Henry-Joyce Cancer Clinic

Nashville, TN United States
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UTMB IDS Pharmacy

Galveston, TX United States
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Utah Cancer Specialists

Murray, UT United States
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Utah Cancer Specialists

Salt Lake City, UT United States
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Pharmacy Department

Camperdown, Australia
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Pharmacie

Brest, France
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Chu Pasteur 1

Nice cedex 1, France
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Centre Paul Strauss

Strasbourg cedex, France
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Saitama Cancer Center

Kita-adachi-gun, Japan
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Asan Medical Center

Seoul, Korea, Republic of
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Ulsan University Hospital

Ulsan, Korea, Republic of
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NHS Grampian

Aberdeen, United Kingdom
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Hollis Cancer Center

Lakeland, FL United States
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IU Health Arnett Cancer Center

Lafayette, IN United States
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Morristown Medical Center

Morristown, NJ United States
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Overlook Medical Center

Summit, NJ United States
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Harrisburg Hospital Pharmacy

Harrisburg, PA United States
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Fox Chase Cancer Center

Philadelphia, PA United States
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Rhode Island Hospital

Providence, RI United States
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GHS Cancer Institute

Easley, SC United States
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GHS Cancer Institute

Greenville, SC United States
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GHS Cancer Institute

Greer, SC United States
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GHS Cancer Institute

Seneca, SC United States
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GHS Cancer Institute

Spartanburg, SC United States
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Clinique Hartmann

Neuilly sur Seine, France
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Hopital Americain de Paris

Neuilly Sur Seine, France
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Samsung Medical Center

Seoul, Korea, Republic of
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Institut Gustave Roussy

Villejuif cedex, France
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Kansas City VA Medical Center

Kansas City, MO United States
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DJL Clinical Research, PLLC

Charlotte, NC United States
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Clinical Trials Pharmacy

Bedford Park, Australia
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Flinders Medical Centre

Bedford Park, Australia
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Farmacia ASMN

Reggio Emilia, Italy
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N. N. Blokhin NMRCO

Moscow, Russian Federation
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Kantonsapotheke Zurich

Schlieren, Switzerland
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Kantonsspital Winterthur

Winterthur, Switzerland
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NHS Lothian

Edinburgh, United Kingdom
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Beverly Hills Cancer Center

Beverly Hills, CA United States
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City of Hope Corona

Corona, CA United States
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Cedars Sinai Medical Center

Los Angeles, CA United States
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City of Hope South Pasadena

South Pasadena, CA United States
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Specialist Global LLC

Hialeah, FL United States
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The West Clinic PC

Corinth, MS United States
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Sutter Infusion Pharmacy

Roseville, CA United States
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Sutter Medical Group

Roseville, CA United States
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Sutter Infusion Pharmacy

Sacramento, CA United States
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Sutter Medical Group

Sacramento, CA United States
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Norton Cancer Institute

Louisville, KY United States
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Norton Hospital

Louisville, KY United States
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Blackrock Clinic

Co. Dublin, Ireland
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CUF Porto

Senhora da Hora, Portugal
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CHU Saint-Andre

Bordeaux Cedex, France
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City of Hope Antelope Valley

Lancaster, CA United States
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PinnacleHealth Cancer Institute

Harrisburg, PA United States
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PinnacleHealth Cancer Institute

Mechancisburg, PA United States
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Recruitment Status: Open


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