Last updated on October 2018

A Study of Rapastinel as Adjunctive Therapy in the Prevention of Relapse in Patients With Major Depressive Disorder


Brief description of study

This study will evaluate the efficacy, safety and tolerability of rapastinel 450 milligrams (mg) intravenous (IV) once weekly or once every 2 weeks versus placebo as an adjunctive treatment to ongoing anti-depressive therapy (ADT) in the prevention of relapse in participants with Major Depressive Disorder (MDD).

Clinical Study Identifier: NCT02951988

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University of Alabama at Birmingham
Birmingham, AL United States

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Harmonex Neuroscience Research
Dothan, AL United States

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NoesisPharma
Phoenix, AZ United States

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University of Arizona Department of Psychiatry
Tucson, AZ United States

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Woodland International Research Group
Little Rock, AR United States

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Woodland Research Northwest
Rogers, AR United States

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California Pharmaceutical Research Institute, Inc
Anaheim, CA United States

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Southern California Research LLC.
Beverly Hills, CA United States

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Radiant Research
Cerritos, CA United States

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ATP Clinical Research Inc.
Costa Mesa, CA United States

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ProScience Research Group
Culver City, CA United States

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Collaborative Neuroscience Network, LLC
Garden Grove, CA United States

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Behavioral Research Specialists, LLC
Glendale, CA United States

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Sun Valley Research Center
Imperial, CA United States

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Synergy Clinical Research Center of Escondido
Lemon Grove, CA United States

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Pharmacology Research Institute
Los Alamitos, CA United States

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Pacific Institute of Medical Research
Los Angeles, CA United States

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Pacific Research Partners; LLC.
Oakland, CA United States

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Excell Research
Oceanside, CA United States

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NRC Research Institute
Orange, CA United States

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University of California, Irvine
Orange, CA United States

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Asclepes Research Centers
Panorama City, CA United States

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Anderson Clinical Research
Redlands, CA United States

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CITrials
Riverside, CA United States

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Artemis Institute for Clinical Research
San Diego, CA United States

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PCSD Feighner Research
San Diego, CA United States

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Thomas M. Shiovitz, M.D., Inc., DBA California Neuroscience Research Medical Group, Inc.,
Sherman Oaks, CA United States

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Viking Clinical Research
Temecula, CA United States

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Pacific Clinical Research Medical
Upland, CA United States

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MCB Clinical Research Center
Colorado Springs, CO United States

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Comprehensive Psychiatric Care
Norwich, CT United States

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Meridien Research
Bradenton, FL United States

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Gulfcoast Clinical Research Center
Fort Myers, FL United States

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Sarkis Clinical Trials
Gainesville, FL United States

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MD Clinical
Hallandale Beach, FL United States

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Reliable Clinical Research
Hialeah, FL United States

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George M. Joseph MD, PA dba JosephCare
Jacksonville Beach, FL United States

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Clinical Neuroscience Solutions, Inc
Jacksonville, FL United States

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Meridien Research
Lakeland, FL United States

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Innovative Clinical Research, Inc
Lauderhill, FL United States

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Innova Clinical Trials Inc.
Miami, FL United States

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Miami Dade Medical Research Institute, LLC
Miami, FL United States

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International Research Associates, LLC
Miami, FL United States

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Research Centers of America
Oakland Park, FL United States

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Medical Research Group of Central Florida
Orange City, FL United States

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Clinical Neuroscience Solutions, Inc
Orlando, FL United States

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Combined Research Orlando Phase I-IV
Orlando, FL United States

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Millenia Psychiatry & Research, Inc
Orlando, FL United States

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Olympian Clinical Research
Tampa, FL United States

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The University of South Florida Board of Trustees, A public Body Corporate, for University of South Florida
Tampa, FL United States

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Institute for Advanced Medical Research
Alpharetta, GA United States

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Radiant Research
Atlanta, GA United States

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Atlanta Center for Medical Research
Atlanta, GA United States

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iResearch Atlanta, LLC
Decatur, GA United States

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Northwest Behavioral Research Center
Marietta, GA United States

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Great Lakes Clinical Trials
Chicago, IL United States

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Alexian Brothers Center for Psychiatric Research
Hoffman Estates, IL United States

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Capstone Clinical Research
Libertyville, IL United States

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AMR - Baber Research, Inc.
Naperville, IL United States

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Goldpoint Clinical Research, LLC
Indianapolis, IN United States

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Psychiatric Associates
Overland Park, KS United States

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Heartland Research Associates
Wichita, KS United States

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Lake Charles Clinical Trials
Lake Charles, LA United States

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Louisiana Clinical Research
Shreveport, LA United States

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J Gary Booker, MD APMC
Shreveport, LA United States

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Sheppard Pratt Health System
Baltimore, MD United States

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Pharmasite Research, Inc
Baltimore, MD United States

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CBH Health
Rockville, MD United States

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Boston Clinical Trials
Boston, MA United States

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ActivMed Practices & Research, Inc.
Methuen, MA United States

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Adams Clinical Trials
Watertown, MA United States

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Coastal Research Associates
Weymouth, MA United States

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University of Massachusetts Medical School
Worcester, MA United States

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Precise Research Centers
Flowood, MS United States

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Millennium Psychiatric Associates
Creve Coeur, MO United States

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Psychiatric Care and Research Center
O'Fallon, MO United States

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St. Charles Psychiatric Associates - Midwest Research Group
Saint Charles, MO United States

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Alivation Research
Lincoln, NE United States

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Altea Research
Las Vegas, NV United States

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Healthy Perspectives - Innovative Mental Health Services. PLLC
Nashua, NH United States

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Hassman Research Institute, LLC
Berlin, NJ United States

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Center for Emotional Fitness
Cherry Hill, NJ United States

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Pharmaceutical Research Associates Inc
Marlton, NJ United States

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Global Medical Institute, LLC
Princeton, NJ United States

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Bio Behavioral Health
Toms River, NJ United States

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Albuquerque Neuroscience, Inc
Albuquerque, NM United States

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SPRI Clinical Trials, Inc
Brooklyn, NY United States

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Radiant Research
Jamaica, NY United States

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Bioscience Research
Mount Kisco, NY United States

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Manhattan Behavioral Medicine
New York, NY United States

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Eastside Comprehensive Medical Center, LLC
New York, NY United States

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The Medical Research Network, LLC
New York, NY United States

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Fieve Clinical Research
New York, NY United States

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Finger Lakes Clinical Research
Rochester, NY United States

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Richmond Behavioral Associates
Staten Island, NY United States

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New Hope Clinical Research Inc.
Charlotte, NC United States

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Richard H. Weisler, MD, PA
Raleigh, NC United States

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Neuro-Behavioral Clinical Research, Inc
Canton, OH United States

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Patient Priority Clinical Site, LLC
Cincinnati, OH United States

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University of Cincinnati
Cincinnati, OH United States

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The Ohio State University Department of Psychiatry
Columbus, OH United States

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Midwest Clinical Research Center LLC
Dayton, OH United States

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Charak Clinical Research Center
Garfield Heights, OH United States

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Lindner Center of Hope
Mason, OH United States

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Professional Psychiatric Services
Mason, OH United States

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IPS Research
Oklahoma City, OK United States

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Red River Medical Research Center, LLC
Oklahoma City, OK United States

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Sooner Clinical Research, Inc
Oklahoma City, OK United States

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Paradigm Research Professionals
Oklahoma City, OK United States

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Summit Research Network
Portland, OR United States

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Lehigh Center for Clinical Research
Allentown, PA United States

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Suburban Research Associates
Media, PA United States

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Dr. Cherian Verghese
Norristown, PA United States

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Carolina Clinical Trials, Inc.
Charleston, SC United States

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Coastal Carolina Research Center, Inc.
Mount Pleasant, SC United States

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Clinical Neuroscience Solutions, Inc
Memphis, TN United States

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Research Strategies of Memphis, LLC
Memphis, TN United States

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Donald J. Garcia, Jr., MD, PA
Austin, TX United States

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Tekton Research
Austin, TX United States

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Community Clinical Research, Inc.
Austin, TX United States

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BioBehavioral Research of Austin
Austin, TX United States

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FutureSearch Trials of Dallas, LP
Dallas, TX United States

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Relaro Medical Trials
Dallas, TX United States

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El Campo Clinical Trials
El Campo, TX United States

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North Texas Clinical Trials
Fort Worth, TX United States

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Earle Research
Houston, TX United States

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Red Oak Psychiatry Associates, PA
Houston, TX United States

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Clinical Trials of Texas
San Antonio, TX United States

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Radiant Research
San Antonio, TX United States

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Family Psychiatry of The Wood
The Woodlands, TX United States

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Grayline Clinical Drug Trials
Wichita Falls, TX United States

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Psychiatric and Behavioral Solutions
Salt Lake City, UT United States

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PRA Health Sciences
Salt Lake City, UT United States

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Department of Psychiatry and Neurobehavioral Sciences, University of Virginia
Charlottesville, VA United States

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Psychiatric Alliance of the Blue Ridge, Inc
Charlottesville, VA United States

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NeuroScience Inc.
Herndon, VA United States

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NorthWest Clinical Research Center
Bellevue, WA United States

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Pacific Institute of Medical Sciences
Bothell, WA United States

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Summit Research Network Seattle LLC
Seattle, WA United States

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Pharmacology Research Institute
Encino, CA United States

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Irvine Center for Clinical Research, Inc
Irvine, CA United States

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Artemis Institute for Clinical Research
San Marcos, CA United States

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Tekton Research
Washington, WA United States

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Advanced Research Institute of Miami
Homestead, FL United States

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Phoenix Medical Research
Prairie Village, KS United States

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BTC of New Bedford
New Bedford, MA United States

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IRIS Research
Smyrna, GA United States

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Eastside Therapeutic Resource
Everett, WA United States

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Houston Clinical Trials, LLC
Bellaire, TX United States

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Sarkis Clinical Trials
Ocala, FL United States

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Synergy San Diego
Lemon Grove, CA United States

Recruitment Status: Closed


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