Last updated on March 2019

Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI


Brief description of study

The purpose of this study is to evaluate the efficacy and safety of LCZ696 titrated to a target dose of 200 mg twice daily, compared to ramipril titrated to a target dose of 5 mg twice daily, in addition to conventional post-AMI treatment, in reducing the occurrence of composite endpoint of CV death, HF hospitalization and outpatient HF (time-to-first event analysis) in post-AMI patients with evidence of LV systolic dysfunction and/or pulmonary congestion, with no known prior history of chronic HF..

Clinical Study Identifier: NCT02924727

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Novartis Investigative Site
Brooklyn, NY United States
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Novartis Pharmaceuticals

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Valhalla, NY United States
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Novartis Pharmaceuticals

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Philadelphia, PA United States
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Novartis Pharmaceuticals

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Seattle, WA United States
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Novartis Pharmaceuticals

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La Plata, Argentina
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Novartis Pharmaceuticals

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Tucuman, Argentina
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Novartis Pharmaceuticals

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Rosario, Argentina
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Novartis Pharmaceuticals

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Linz, Austria
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Novartis Pharmaceuticals

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Pernik, Bulgaria
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Novartis Pharmaceuticals

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Toronto, ON Canada
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Novartis Pharmaceuticals

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Terrebonne, QC Canada
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Novartis Pharmaceuticals

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Shengyang, China
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Novartis Pharmaceuticals

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Medellin, Colombia
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Novartis Pharmaceuticals

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Bucaramanga, Colombia
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Novartis Pharmaceuticals

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Bogota, Colombia
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Novartis Pharmaceuticals

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Zagreb, Croatia
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Novartis Pharmaceuticals

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HUS, Finland
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Novartis Pharmaceuticals

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Paris, France
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Novartis Pharmaceuticals

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Bremen, Germany
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Novartis Pharmaceuticals

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Essen, Germany
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Novartis Pharmaceuticals

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Esslingen, Germany
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Novartis Pharmaceuticals

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Freiburg, Germany
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Novartis Pharmaceuticals

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Guetersloh, Germany
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Novartis Pharmaceuticals

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Hennigsdorf, Germany
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Novartis Pharmaceuticals

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Kiel, Germany
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Koeln-Nippes, Germany
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Langen, Germany
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Leipzig, Germany
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Novartis Pharmaceuticals

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Leverkusen, Germany
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Novartis Pharmaceuticals

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Moenchengladbach, Germany
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Novartis Pharmaceuticals

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Neuwied, Germany
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Oldenburg, Germany
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Ruesselsheim, Germany
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Novartis Pharmaceuticals

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Vechta, Germany
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Novartis Pharmaceuticals

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Villingen-Schwenningen, Germany
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Novartis Pharmaceuticals

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Witten, Germany
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Novartis Pharmaceuticals

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Wuerzburg, Germany
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Novartis Pharmaceuticals

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Sanremo, Italy
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Novartis Pharmaceuticals

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Lima, Peru
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Novartis Pharmaceuticals

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Warszawa, Poland
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Novartis Pharmaceuticals

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Targu Mures, Romania
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Novartis Pharmaceuticals

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Timisoara, Romania
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Novartis Pharmaceuticals

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Baia Mare, Romania
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Novartis Pharmaceuticals

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Craiova, Romania
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Novartis Pharmaceuticals

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Barnaul, Russian Federation
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Novartis Pharmaceuticals

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Kemerovo, Russian Federation
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Novartis Pharmaceuticals

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Rostov on Don, Russian Federation
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Novartis Pharmaceuticals

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Yekaterinburg, Russian Federation
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Novartis Pharmaceuticals

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Taipei, Taiwan
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Novartis Pharmaceuticals

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Taoyuan, Taiwan
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Novartis Pharmaceuticals

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Yilan, Taiwan
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Novartis Pharmaceuticals

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Frederick, MD United States
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Novartis Pharmaceuticals

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Southfield, MI United States
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Novartis Pharmaceuticals

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Hackensack, NJ United States
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Novartis Pharmaceuticals

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Chapel Hill, NC United States
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Novartis Pharmaceuticals

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Charlotte, NC United States
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Novartis Pharmaceuticals

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Santa Fe, Argentina
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Novartis Pharmaceuticals

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Halifax, NS Canada
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Novartis Pharmaceuticals

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Sainte Foy, QC Canada
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Novartis Pharmaceuticals

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Koeln, Germany
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Novartis Pharmaceuticals

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Neuss, Germany
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Novartis Pharmaceuticals

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Zalaegerszeg, Hungary
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Novartis Pharmaceuticals

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Lower Galilee, Israel
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Novartis Pharmaceuticals

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Saronno, Italy
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Novartis Pharmaceuticals

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Pavia, Italy
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Novartis Pharmaceuticals

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Pitesti, Romania
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Novartis Pharmaceuticals

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Iasi, Romania
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Novartis Pharmaceuticals

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Suceava, Romania
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Novartis Pharmaceuticals

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Bucharest, Romania
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Novartis Pharmaceuticals

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Bucuresti, Romania
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Murmansk, Russian Federation
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N.Novgorod, Russian Federation
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S.-Petersburg, Russian Federation
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Tomsk, Russian Federation
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Helsingborg, Sweden
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Novartis Pharmaceuticals

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Curitiba, Brazil
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Sao Jose do Rio Preto, Brazil
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Novartis Pharmaceuticals

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Sao Paulo, Brazil
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Novartis Pharmaceuticals

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Kardzhali, Bulgaria
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Vadodara, India
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Novartis Pharmaceuticals

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Pune, India
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Novartis Pharmaceuticals

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Lublin, Poland
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Novartis Pharmaceuticals

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Belfast, United Kingdom
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Novartis Pharmaceuticals

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Kochi, India
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Novartis Pharmaceuticals

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Iloilo city, Philippines
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Novartis Pharmaceuticals

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Cluj Napoca, Romania
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Novartis Pharmaceuticals

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Sibiu, Romania
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Novartis Pharmaceuticals

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Porto Alegre, Brazil
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Novartis Pharmaceuticals

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Halle Saale, Germany
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Novartis Pharmaceuticals

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Oradea, Romania
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Novartis Pharmaceuticals

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Braila, Romania
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Novartis Pharmaceuticals

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Arad, Romania
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Novartis Pharmaceuticals

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Brasov, Romania
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Novartis Pharmaceuticals

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St Petersburg, Russian Federation
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Novartis Pharmaceuticals

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Istanbul, Turkey
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Novartis Pharmaceuticals

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Tianjin, China
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Novartis Pharmaceuticals

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Haifa, Israel
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Novartis Pharmaceuticals

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Saint Petersburg, Russian Federation
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Novartis Pharmaceuticals

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Sivas, Turkey
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Novartis Pharmaceuticals

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Los Angeles, CA United States
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Novartis Pharmaceuticals

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Boise, ID United States
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Novartis Pharmaceuticals

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Clackamas, OR United States
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Novartis Pharmaceuticals

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Erie, PA United States
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Novartis Pharmaceuticals

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Blumenau, Brazil
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Novartis Pharmaceuticals

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Karamsad, India
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Novartis Pharmaceuticals

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Izmir, Turkey
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Novartis Pharmaceuticals

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Kocaeli, Turkey
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Novartis Pharmaceuticals

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Hattiesburg, MS United States
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Novartis Pharmaceuticals

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New Delhi, India
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Novartis Pharmaceuticals

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Mumbai, India
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Novartis Pharmaceuticals

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Tel Aviv, Israel
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Novartis Pharmaceuticals

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Manila, Philippines
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Novartis Pharmaceuticals

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Fortaleza, Brazil
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Novartis Pharmaceuticals

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Beijing, China
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Novartis Pharmaceuticals

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Petach Tikva, Israel
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Novartis Pharmaceuticals

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Orange, CA United States
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Novartis Pharmaceuticals

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Goiania, Brazil
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Novartis Pharmaceuticals

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Belo Horizonte, Brazil
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Novartis Pharmaceuticals

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Campina Grande do Sul, Brazil
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Novartis Pharmaceuticals

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Chang Chun, China
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Novartis Pharmaceuticals

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Grenoble Cédex 9, France
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Novartis Pharmaceuticals

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Quezon City, Philippines
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Novartis Pharmaceuticals

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Bialystok, Poland
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Novartis Pharmaceuticals

Novartis Investigative Site
Lubin, Poland
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Recruitment Status: Open


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