Last updated on May 2020

Sustainability of Vaginal Estrogen Therapy in Postmenopausal Women

Brief description of study

Sustainability of vaginal ultra-low dose estrogen therapy in postmenopausal women

Detailed Study Description

Within this trial 50 postmenopausal women receive a vaginal estrogen therapy as treatment for symptomatic vaginal atrophy. The sustainability of vaginal estrogen therapy after the end of therapy has not yet been investigated.

All participants will be asked to come for the following 7 visits.

  • Visit 1: Standard Gynecological examination; Inclusion and exclusion criteria check
  • Visit 2: Handing out of Gynoflor (estrogen) for a 6 weeks treatment.
  • Visit 3 (Study Start): After using the vaginal estrogen for 6 weeks, a vaginal swap will be done to measure the vaginal maturation index (VMI). The participants will also receive a questionnaire to define some subjective parameters. The parameters measured at visit 1 will count as reference. The estrogen therapy will now be sustained.
  • Visit 4-6: Measuring of the VMI and handing out the questionnaires to define subjective parameters.

Clinical Study Identifier: NCT02887885

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