Site networks IACT Health and LMC Manna Research have combined their operations in a strategic alliance, joining forces to create one of the largest research networks in North America.

The pair, based in the U.S. and Canada, respectively, said that their new extensive site network brings more than 40 sites, 1.5 million potential participants and 150 active investigators together.

IACT Health said that it is the largest network of research sites in the southeastern U.S., conducting clinical trials in more than 30 therapeutic areas as well as routine, urgent and emergency healthcare. A Tufts University assessment found that the company’s enrollment rates were more than 212 percent higher than the average research site.

LMC Manna claims to be Canada’s largest clinical research network and uses a networkwide decentralized technology system in its trials. The company has conducted more than 2,000 clinical trials to date and more than 4,000 patient randomizations since 2013.