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Pipeline
| Company | Drug/Device | Medical Condition | Status |
|---|---|---|---|
| Agenus Bristol Myers Squibb |
AGEN1777 | advanced solid tumors | IND approved by the FDA |
| Cullinan Oncology | CLN-619 | solid and liquid tumors | IND approved by the FDA |
| Eucure Biopharma | YH001 | advanced nonsmall-cell lung cancer and hepatocellular carcinoma | IND approved by the FDA for phase 2 trial |
| Eucure Biopharma | YH003 | PD-1-resistant unresectable/metastatic melanoma and pancreatic ductal adenocarcinoma | IND approved by the FDA for phase 2 trial |
| HDT Bio | HDT-301 COVID-19 RNA vaccine | SARS-CoV-2 and variants | IND approved by the FDA |
| Immunic | IMU-838 | relapsing-remitting multiple sclerosis | IND approved by the FDA for phase 3 trial |
| Immunic | IMU-838 | progressive multiple sclerosis | IND approved by the FDA for phase 2 trial |
| Sirnaomics | STP707 | advanced solid tumors | IND approved by the FDA |
| Sorrento Therapeutics | Resiniferatoxin (RTX) | moderate-to-severe pain from osteoarthritis of the knee | IND approved by the FDA for phase 2 trial |
| Vect-Horus RadioMedix |
68Ga-RMX-VH | glioblastoma multiforme diagnostic | exploratory IND approved by the FDA |
| Antengene | selinexor | myelofibrosis | IND approved by China's National Medical Products Administration |
| SciSparc | SCI-110 | Alzheimer's disease and agitation | approval received from the Israeli Ministry of Health and Helsinki Committee for a phase 2a trial |
| CytoSorbents | ticagrelor | cardiopulmonary bypass circuit during cardiothoracic surgery | IDE approved by the FDA |
| Genentech | intravenous Actemra (tocilizumab) | COVID-19 in hospitalized adults and pediatric patients (two years of age and older) who are receiving systemic corticosteroids and require supplemental oxygen, noninvasive or invasive mechanical ventilation, or extracorporeal membrane oxygenation | Emergency Use Authorization granted by the FDA |
| Galderma | Restylane Contour | cheek augmentation and midface contour deficiencies | approved by the FDA |
| Jazz Pharmaceuticals | Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn) | acute lymphoblastic leukemia or lymphoblastic lymphoma in pediatric and adult patients one month and older who have developed hypersensitivity to E. coli-derived asparaginase | approved by the FDA |
| Lupin Pharmaceuticals | Solosec (secnidazole) | trichomoniasis vaginalis | approved by the FDA for expanded indication |
| Merck | Keytruda (pembrolizumab) | patients with locally advanced cutaneous squamous-cell carcinoma that is not curable by surgery or radiation | approved by the FDA for expanded indication |
| Siemens Healthineers | Magnetom Free.Max 80 cm |
lightweight magnetic resonance scanner | cleared for marketing by the FDA |
| Bristol Myers Squibb | Opdivo (nivolumab) plus Yervoy (ipilimumab) | mismatch repair-deficient or microsatellite instability-high metastatic colorectal cancer after prior fluoropyrimidine-based combination chemotherapy | approved by the European Commission |
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