Changes in COVID-19-related research (CIR) submissions surged suddenly in Spring 2020, according to data from the WCG Knowledge Base, as sponsors and researchers quickly adjusted research plans with shifts to virtual study visits, remote measurement of study endpoints and modifications to informed consent processes. The surge peaked at 58 percent of all CIR submissions in April. By the end of 2020, however, COVID-19-related CIRs made up only 5 percent of all submissions.

In 2021, a small number of trials continue to adjust operationally around changing pandemic precautions, WCG says, shifting study visits and assessments from remote and virtual encounters back to in-person visits.