• SKIP TO CONTENT
  • SKIP NAVIGATION
  • Patient Resources
    • COVID-19 Patient Resource Center
    • Clinical Trials
    • Search Clinical Trials
    • Patient Notification System
    • What is Clinical Research?
    • Volunteering for a Clinical Trial
    • Understanding Informed Consent
    • Useful Resources
    • FDA Approved Drugs
  • Professional Resources
    • Research Center Profiles
    • Clinical Trial Listings
    • Market Research
    • FDA Approved Drugs
    • Training Guides
    • Books
    • eLearning
    • Events
    • Newsletters
    • White Papers
    • SOPs
    • eCFR and Guidances
  • White Papers
  • Trial Listings
  • Advertise
  • COVID-19
  • iConnect
  • Sign In
  • Create Account
  • Sign Out
  • My Account
Home » Sponsors, Sites Continue to Deal With Trial Disruptions

Sponsors, Sites Continue to Deal With Trial Disruptions

April 20, 2020

Pharma companies and CROs continue to announce temporary suspensions of patient recruitment during the COVID-19 pandemic, but some companies are pivoting themselves and re-positioning their efforts toward studying possible treatments for the virus:

  • Restrictions to control the spread of COVID-19 in in Singapore has led Aslan Pharmaceuticals to pause recruitment of new patients into its study of ASLAN004, an anti-IL-13R?1 antibody and potential treatment for moderate to severe atopic dermatitis. The Singapore-based biotech says it is still on track to deliver interim results of the trial’s three dose cohorts in the third quarter.
  • San Francisco, Calif.-biopharma company CytomX has halted enrollment of new patients and paused activation of new sites for its phase 1/2 study of cancer investigational drug CX-2009. CytomX also terminated its PROCLAIM-CX-072-002 melanoma study in response to the COVID-19 pandemic. The study planned to examine a combined therapeutic regimen consisting of anti-PD-L1 Probody CX-072 plus Bristol Myers Squibb’s ipilimumab.
  • CRO company IQVIA has initiated a matchmaking trial service, which is designed to accelerate vaccine development and treatment of COVID-19.
  • Moderna has paused enrollment for its phase 1 trials of methylmalonic acidemia and propionic acidemia. The Cambridge, Mass.-based company has also de-escalated its pediatric respiratory vaccine study and has suspended enrollment of new seropositive pediatric patients for the ongoing human metapneumovirus/parainfluenza phase 3 study. Moderna has funneled most of its energy into a phase 1 clinical trial of an mRNA vaccine candidate against COVID-19. The company’s COVID-19 vaccine trial has recently dosed its first patient.
  • Outlook Therapeutics announced that the recruitment for its NORSE 2 ongoing trial of bevacizumab-vikg, an ophthalmic formulation of bevacizumab, has slowed because of the global health crisis. Additional safety protocols to reduce transmission of the virus have resulted in the temporary closure of some trial sites. The final enrollment could be delayed by one to three months, according to Outlook estimates. NORSE 2 will continue to screen and treat participating patients.
  • Parexel has announced that it has temporarily stopped screening new patients and health participants in UK clinical trials because of the restrictions posed by COVID-19.
COVID-19
  • Related Directories

    Olumiant (baricitinib)

    Veklury (remdesivir)

    Comirnaty (COVID-19 Vaccine, mRNA)

Upcoming Events

  • 16Feb

    Fundamentals of FDA Inspection Management: Reduce Anxiety, Increase Inspection Success

  • 21May

    WCG MAGI Clinical Research Conference – 2023 East

Featured Products

  • Spreadsheet Validation: Tools and Techniques to Make Data in Excel Compliant

    Spreadsheet Validation: Tools and Techniques to Make Data in Excel Compliant

  • Surviving an FDA GCP Inspection

    Surviving an FDA GCP Inspection: Resources for Investigators, Sponsors, CROs and IRBs

Featured Stories

  • Revamp-360x240.png

    Califf Calls for Major Evidence Generation Revamp, Experts’ Opinions Differ

  • AskTheExpertsGreen-360x240.png

    Ask the Experts: Managing Investigational Products

  • SurveywBlueBackground-360x240.png

    Survey Outlines Site Challenges, Successes on Diversity

  • PatientCentricity-360x240.png

    Site Spotlight: DM Clinical Shows Patient Centricity Doesn’t Have to Break the Bank

Standard Operating Procedures for Risk-Based Monitoring of Clinical Trials

The information you need to adapt your monitoring plan to changing times.

Learn More Here
  • About Us
  • Contact Us
  • Privacy Policy
  • Do Not Sell or Share My Data

Footer Logo

300 N. Washington St., Suite 200, Falls Church, VA 22046, USA

Phone 617.948.5100 – Toll free 866.219.3440

Copyright © 2023. All Rights Reserved. Design, CMS, Hosting & Web Development :: ePublishing