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Home » Adaptive Trial Design: Putting in the Work Up Front
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Adaptive Trial Design: Putting in the Work Up Front

November 22, 2019
Elizabeth Tilley Hinkle

Adaptive trial designs can produce results more quickly and identify patient populations more clearly. But the savings in time and effort during the trial is balanced by the work that must be done in the design stage.

Unlike conventional studies, adaptive clinical trial design calls for ongoing analysis of data and modification of key trial parameters in response to the results. The adaptive trial model requires more extensive protocol planning — regular data analysis points need to be identified and rules created for making decisions about modifications before the trial begins.

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