• SKIP TO CONTENT
  • SKIP NAVIGATION
  • Patient Resources
    • COVID-19 Patient Resource Center
    • Clinical Trials
    • Search Clinical Trials
    • Patient Notification System
    • What is Clinical Research?
    • Volunteering for a Clinical Trial
    • Understanding Informed Consent
    • Useful Resources
    • FDA Approved Drugs
  • Professional Resources
    • Research Center Profiles
    • Clinical Trial Listings
    • Market Research
    • FDA Approved Drugs
    • Training Guides
    • Books
    • eLearning
    • Events
    • Newsletters
    • JobWatch
    • White Papers
    • SOPs
    • eCFR and Guidances
  • White Papers
  • Trial Listings
  • Advertise
  • COVID-19
  • iConnect
  • Sign In
  • Create Account
  • Sign Out
  • My Account
Home » Nearly 90 medicines and vaccines in development for HIV/AIDS

Nearly 90 medicines and vaccines in development for HIV/AIDS

December 2, 2011
CenterWatch Staff

America’s biopharmaceutical research companies are testing 88 medicines and vaccines to treat or prevent HIV/AIDS and related conditions, according to a report by the Pharmaceutical Research and Manufacturers of America (PhRMA).

While HIV/AIDS is one of the most devastating diseases affecting people around the world, overall global growth of the disease has stabilized, the number of new infections has been steadily declining, and there are fewer AIDS-related deaths due to the availability of different therapies, such as antiretrovirals, and an enhanced focus on prevention.

Over the past three decades, more than 30 medicines have been approved to treat HIV/AIDS. While these medicines have helped to prolong the lives of HIV-infected patients, it is not enough. America’s biopharmaceutical researchers are focusing on improved treatment regimens, more targeted therapies, and intensifying their efforts to develop preventative vaccines. The International AIDS Vaccine Initiative estimates that a vaccine that is 50% effective and given to only 30% of the population could reduce new HIV infections by 24% over 15 years. Of the 88 medicines and vaccines in development, 49 are antivirals and 27 are vaccines. All of the medicines are either in clinical trials or awaiting review by the U.S. Food and Drug Administration. They include:

• An antisense gene therapy that uses genetic material derived from HIV-1 itself to remove disease-causing aspects of the virus.

• A transdermal vaccine comprised of DNA plasmids that helps suppress virus replication and destroys HIV-infected cells.

• One treatment in a new class of medicines is intended to prevent the HIV virus from attaching to new cells and breaking through the cell membrane.

HIV/AIDS remains a formidable foe and worldwide epidemic. “The disease poses a complex problem, and we in the biopharmaceutical research industry know as well as anyone that it will require a complex solution,” said PhRMA president and CEO John J. Castellani. “We will find a cure eventually, but in the meantime we continue our efforts to develop new preventative approaches and treatments, so the millions of patients suffering today have a hope of a better tomorrow.”

The Pharmaceutical Research and Manufacturers of America (PhRMA) represents the country’s leading pharmaceutical research and biotechnology companies devoted to inventing medicines that allow patients to live longer, healthier and more productive lives. PhRMA companies are leading the way in the search for new cures. PhRMA members alone invested an estimated $49.4 billion in 2010 in discovering and developing new medicines. Industry-wide research and investment reached a record $67.4 billion in 2010.

 

Upcoming Events

  • 17May

    Three Data Trends to Consider Now When Developing Your Decentralized Clinical Trial Strategy

  • 24May

    Powering an Effective Oversight Strategy with Clinical and Operational Insights

  • 25May

    2022 WCG Avoca Quality & Innovation Summit: Own the Future

  • 28Jun

    Effective Root Cause Analysis and CAPA Investigations for the Life Sciences

  • 16Oct

    WCG MAGI's Clinical Research Hybrid Conference - 2022 West

Featured Products

  • Spreadsheet Validation: Tools and Techniques to Make Data in Excel Compliant

    Spreadsheet Validation: Tools and Techniques to Make Data in Excel Compliant

  • Surviving an FDA GCP Inspection

    Surviving an FDA GCP Inspection: Resources for Investigators, Sponsors, CROs and IRBs

Featured Stories

  • Protocol-360x240.png

    Avoid Deviations by Making Protocol Review a Team Effort

  • SelectionProcess-360x240.png

    Give Us a Voice: Sites Clamor for a Say on Vendor Selection

  • Convince-360x240.png

    Use Data and Details to Convince Site Leadership to Add Staff

  • AsktheExpertsBadge-360x240.png

    Ask the Experts: Listing Trial Staff and Others on the Statement of Investigator

Standard Operating Procedures for Risk-Based Monitoring of Clinical Trials

The information you need to adapt your monitoring plan to changing times.

Learn More Here
  • About Us
  • Contact Us
  • Privacy Policy
  • Do Not Sell My Personal Information

Footer Logo

300 N. Washington St., Suite 200, Falls Church, VA 22046, USA

Phone 617.948.5100 – Toll free 866.219.3440

Copyright © 2022. All Rights Reserved. Design, CMS, Hosting & Web Development :: ePublishing