Emmaus Medical completes enrollment for phase III sickle cell disease trial
Emmaus Medical, a specialty pharmaceutical and regenerative medicine company, has completed patient enrollment for its phase III clinical trial to study L-glutamine as a treatment for sickle cell disease.
“The completion of enrollment is a significant milestone for our company and the sickle cell community, moving one step closer to potentially bringing the first widely available treatment to patients throughout the world who suffer from this debilitating disease,” said Yutaka Niihara, M.D., MPH, founder and CEO of Emmaus Medical. “Without the generous support of our investors, who have contributed nearly $30 million to advance this treatment for sickle cell disease, we would not have been able to progress this far.”
The phase III trial is a prospective, randomized, double-blind, placebo-controlled, parallel-group, multi-center study designed to evaluate the safety and efficacy of L-glutamine as a therapy for sickle cell anemia and β0-thalassemia. Over 225 patients have been enrolled in the study across 31 sites in the U.S.
L-glutamine therapy for sickle cell disease and β0-Thalassemia is a patent protected treatment, whose research was led by Dr. Niihara and investigators at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center. The therapy has Orphan Drug status in the U.S. and Europe and Fast Track designation from the FDA.