VelaLabs, a provider of analytical services to the global biopharmaceutical industry, and Evercyte, a producer of standardized, relevant cell systems, are cooperating to commercialize immortalized target cells for the characterization of biosimilars in a GMP environment.
Combining Vela’s experience in the characterization of biosimilars with Evercyte’s know-how to immortalize relevant primary target cells, the partnership will provide product-tailored bioassays. A VEGF-responsive cell line (HUVEC) already has been established for potency testing of bevacizumab (Avastin) biosimilars.
“In terms of regulatory compliance, stable cell lines are much more reliable than primary cells. We are pleased to bring bioassays based on this distinct advantage to our customers in the global biopharmaceutical industry,” said Dr. Andreas Nechansky, co-founder and chief operating officer of VelaLabs. “Making immortalized cell lines available for GMP testing complements the broad analytical method portfolio we have developed to serve the needs of manufacturers of biopharmaceuticals and biosimilars worldwide.”
“The need of product relevant cell lines that can be standardized is ever increasing in view of restrictions on the use of laboratory animal as well as the increased demand for analyzing the biological activity of biosimilars and biopharmaceuticals,” said Dr. Johannes Grillari, co-founder and chief scientific officer of Evercyte. “Therefore, our cooperation aims to introduce Evercyte’s cell lines into the GMP environment and to establish novel, relevant cell lines, including innovative reporter cell lines, for specific biopharmaceuticals, again for use under GMP conditions.”