Trial Information

Summary: To assess the mucosal immune response to genital herpes simplex virus before and after treatment and determine if cervicovaginal fluid from herpes-infected women affects HIV in vitro

We are seeking women ages 18-50 with active genital herpes lesions who are willing to donate a sample of their vaginal fluid for a research study. The purpose of this study is to see if treating genital herpes causes a change in the cells of the vagina that protect against infection. Subjects will be reimbursed for time and travel. Your part in the study will last two weeks. For information call 212-241-6395 or 212-241-5890
Compensation Provided

Patient Inclusion/Exclusion Criteria:

Women ages 18-50 with active genital lesions.
Able and willing to provide informed consent to participate in the study. Agree to abstain from sexual intercourse and to not douche or use vaginal products for the duration of the two week study. Agree to anti-HSV therapy.

Pregnant, breastfeeding, menopausal, HIV, anti-HSV therapy in the past 2 weeks. Currently menstruating at the time of visit. Concurrent vaginitis, urinary tract infection or sexually transmitted infection including bacterial vaginosis, trichomoniasis, candidiasis, chlamydia, gonorrhea, or syphilis within one month prior to or at screening. Intercourse within 48 hours of enrollment. Hypersensitivity to acyclovir.

If you would like to learn more about participating in this study, please send an e-mail message using the form below.