Trial Information

Summary: COG AHOD0031: A Phase III Group-Wide Study of Dose-Intensive Response-Based Chemotherapy and Radiation Therapy for Children and Adolescents with Newly Diagnosed Intermediate Risk Hodgkin Disease

You have/Your child has been asked to participate in this research study because you have/your child has been recently diagnosed with Hodgkin disease, a cancer of the lymph system. There are several purposes for this research study: 1. To find out if more therapy for slow early responders is better than the standard therapy; 2. To find out if subjects who have an early complete response to chemotherapy can be treated successfully without radiation therapy; 3. To find out if certain factors like symptoms, age, sex, and blood test results predict how well a subject will respond to treatment; 4. To find out which late effects occur after Hodgkin disease treatment and how often they occur; and 5. To collect information on how PET scans (a radiation scan that helps to determine the activity of tumor in the body) provide useful information about which places in the body are affected by Hodgkin Disease in children and teenagers. You/your child will be treated on this study for about 4-6 months. However, subjects will continue to have follow-up medical tests for 10 or more years after treatment so that researchers can continue to observe you/your child for signs of relapse (the cancer coming back) or any long-term side effects of treatment. In addition, general follow-up information will be obtained on your/your child's health status once a year throughout your/your child's lifetime.

Patient Inclusion/Exclusion Criteria:

- See http://clinicaltrials.coh.org for additional information.

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Trial listings updated: October 6, 2008 at 2:28:24 PM