Trial Information

Summary: Treatment of Obsessive-Compulsive Disorder (OCD) with Transcranial Magnetic Stimulation (TMS)

This study is a research trial of an outpatient, non-medication, non-ivasive investigational treatment called Transcranial Magnetic Stimulation (TMS). TMS applies a magnetic field to the brain for a brief period of time. TMS is a procedure that involves 30 minute-long daily sessions every weekday for a series of weeks. We are testing whether TMS can treat obsessive-compulsive disorder (OCD).

Participants will be randomly assigned to receive either active rTMS or sham (placebo) rTMS. If patients receive sham and/or do not improve, they have the option of receiving real TMS in the second phase of the study.

Inclusion:

• 18-70 years old
• Current obsessive-compulsive disorder for at least a year.
• Previous or current treatment with an adequate trial of medication ( a serotonin reuptake inhibitor, or SSRI) or unable to tolerate the side effects of medication.
• Able to commute to NYC for daily treatments (Monday - Friday) for a series of weeks.

Exclusion:

• Prior treatment with TMS or Deep Brain Stimulation (DBS).
• Metal objects in head.
• Pregnancy / breastfeeding.
• Neurological disorder, history of seizure or stroke.
• Current use of medications that may interact with TMS (e.g., clomipramine, anticonvulsants, benzodiazepines).

For more information,

If you would like to learn more about participating in this study, please send an e-mail message using the form below.