Trial Information

Summary: Genotype and Phenotype of Brainstem Injury in Autism, Project IV: Gene-environment interactions in a population exposed to a teratogen associated with autism

Children exposed to valproic acid before birth:
The Genetics Unit of Massachusetts General Hospital is looking for children who were exposed to the anticonvulsant drug, valproate, before birth. There has been some concern that prenatal exposure to this drug increases the risk for Autism Spectrum Disorders (ASDs) in some children. We are studying whether the effects of exposure to valproate during pregnancy depend on the child’s genetic makeup (the presence of certain genes). To participate in this study, the children must be at least 2 years of age. The research study would require only a one-day visit as an outpatient free of charge. For some children, the visit would be shorter than an entire day. Participants will receive $100 for his/her participation, and travel expenses will be reimbursed. If you are interested in participating or would like more information, please contact Uma Deshmukh by calling 617-724-1252 or by e-mail at udeshmukh@partners.org. You can also call us at our toll-free number 1-866-354-1523.

If you would like to learn more about participating in this study, please send an e-mail message using the form below.